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Developmental CellDiscovery in worms by Queen's researchers points to more targeted cancer treatment
Researchers at Queen's University have found a link between two genes involved in cancer formation in humans, by examining the genes in worms. The groundbreaking discovery provides a foundation for how tumor-forming genes interact, and may offer a drug target for cancer treatment.
National Cancer Institute of Canada, Canadian Institutes of Health ResearchContact: Jeff Drake
jeff.drake@queensu.ca
613-533-2877
Queen's University
Cancer ResearchDrug shrinks lung cancer tumors in mice
A potential new drug for lung cancer has eliminated tumors in 50 percent of mice in a new study published today in the journal Cancer Research. In the animals, the drug also stopped lung cancer tumors from growing and becoming resistant to treatment. The authors of the research, from Imperial College London, are now planning to take the drug into clinical trials, to establish whether it could offer hope to patients with an inoperable form of lung cancer.
Cancer Treatment and Research Trust, Cancer Research UK, UK Department of HealthContact: Lucy Goodchild
lucy.goodchild@imperial.ac.uk
44-020-759-46702
Imperial College London
Proceedings of the National Academy of SciencesScientists successfully reprogram blood cells
Researchers have transplanted genetically modified hematopoietic stem cells into mice so that their developing red blood cells produce a critical lysosomal enzyme -- preventing or reducing organ and central nervous system damage from the often-fatal genetic disorder Hurler's syndrome.
National Insitutes of HealthContact: Jim Feuer
jim.feuer@cchmc.org
513-636-4656
Cincinnati Children's Hospital Medical Center
Proceedings of the National Academy of SciencesFDA-approved drugs eliminate, prevent cervical cancer in mice
Researchers at the University of Wisconsin-Madison School of Medicine and Public Health have eliminated cervical cancer in mice with two FDA-approved drugs currently used to treat breast cancer and osteoporosis.
Contact: Dian Land
dj.land@hosp.wisc.edu
608-261-1034
University of Wisconsin-Madison
Proceedings of the National Academy of SciencesStem cells restore cognitive abilities impaired by brain tumor treatment, UCI study finds
Human embryonic stem cells could help people with learning and memory deficits after radiation treatment for brain tumors, suggests a new UC Irvine study.
California Institute for Regenerative Medicine, National Institutes of HealthContact: Jennifer Fitzenberger
jfitzen@uci.edu
949-824-3969
University of California - Irvine
Cancer Epidemiology, Biomarkers & PreventionScientists uncover new key to the puzzle of hormone therapy and breast cancer
The use of postmenopausal hormone therapy has decreased over time in the United States, which researchers suggest may play a key role in the declining rate of atypical ductal hyperplasia, a known risk factor for breast cancer.
Contact: Tara Yates
tara.yates@aacr.org
267-646-0558
American Association for Cancer Research
Source - Science Daily:
November 10, 2009 — Human embryonic stem cells could help people with learning and memory deficits after radiation treatment for brain tumors, suggests a new ...
http://www.sciencedaily.com/releases/2009/11/091109173600.htm
Radiation After Surgery Reduces Chance Of Melanoma Returning
November 10, 2009 — High-risk melanoma patients who are treated with radiation after surgery have a significantly lower risk of their cancer returning to the lymph nodes (19 percent), compared to those patients who do ...
http://www.sciencedaily.com/releases/2009/11/091102103336.htm
Some Malignant Tumors Can Be Shut Down After All
November 10, 2009 — More than half of all human cancers have mutations that disable a protein called p53. When cells lose p53, tumors grow aggressively and often cannot be treated. But a new study may offer a way to ...
http://www.sciencedaily.com/releases/2009/11/091109121332.htm
Blood Test Identifies Women At Risk From Alzheimer's
November 9, 2009 — Middle-aged women with high levels of a specific amino acid in their blood are twice as likely to suffer from Alzheimer's many years later, reveals new research from
http://www.sciencedaily.com/releases/2009/11/091106095638.htm
Breast Density Associated With Increased Risk Of Cancer Recurrence
November 9, 2009 — A new study finds that women treated for breast cancer are at higher risk of cancer recurrence if they have dense breasts. The study's results indicate that breast cancer patients with dense breasts ...
http://www.sciencedaily.com/releases/2009/11/091109090427.htm
Gene Therapy Stalls Development Of Huntington's Disease In Mice
November 9, 2009 — Researchers at the California Institute of Technology have shown that a highly specific intrabody (an antibody fragment that works against a target inside a cell) is capable of stalling the ...
http://www.sciencedaily.com/releases/2009/10/091031002310.htm
Scientists Reveal How Induced Pluripotent Stem Cells Differ From Embryonic Stem Cells
November 9, 2009 — The same genes that are chemically altered during normal cell differentiation, as well as when normal cells become cancer cells, are also changed in stem cells that scientists derive from adult ...
http://www.sciencedaily.com/releases/2009/11/091105092615.htm
Approved Lymphoma Drug Shows Promise In Early Tests Against Bone Cancer
November 9, 2009 — A drug already approved for the treatment of lymphoma may also slow the growth of the most deadly bone cancer in children and teens, according to an early-stage ...
http://www.sciencedaily.com/releases/2009/11/091105102716.htm
Unravelling The Pathology Of Dementia
November 9, 2009 — Combination therapies to tackle multiple changes in the brain may be needed to combat the growing problem of dementia in aging societies, according to a new ...
http://www.sciencedaily.com/releases/2009/11/091110065911.htm
Scientists Explain Binding Action Of 2 Key HIV Antibodies; Could Lead To New Vaccine Design
November 9, 2009 — A very close and detailed study of how the most robust antibodies work to block the HIV virus as it seeks entry into healthy cells has revealed a new direction for researchers hoping to design an ...
http://www.sciencedaily.com/releases/2009/11/091109173730.htm
'Optical Biopsy' For Breast Cancer Increasingly Accurate, Research Finds
November 8, 2009 — Most biopsies following mammograms reveal benign abnormalities, not cancer. But women may not have to endure the medical costs, stress and potential complications that accompany such invasive ...
http://www.sciencedaily.com/releases/2009/11/091105121213.htm
Health Highlights: Nov. 10, 2009
- Vets Struggle to Get Counseling/Substance Abuse Treatment: Survey
- Scientists Weigh Boundaries For Human-Animal DNA Trials
- Basketball Legend Abdul-Jabbar Treated for Leukemia
- Maclaren Strollers Pose Amputation Hazard
Anemia Drugs May Cause Deadly Blood Clots
Study raises more concerns about common treatment for chemo patients.
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