Source - EurekAlert – Biology:
Public Release: 16-Oct-2009
New findings on the formation of body pigment <http://ki.se/ki/jsp/polopoly.jsp?l=en&d=130&a=85186&newsdep=130>
The skin's pigment cells can be formed from completely different cells than has hitherto been thought, a new study from the Swedish medical university Karolinska Institutet shows. The results, which are published in the journal Cell, also mean the discovery of a new kind of stem cell.
Contact: Press Officer Katarina Sternudd
katarina.sternudd@ki.se <mailto:katarina.sternudd@ki.se>
46-852-483-895
Karolinska Institutet <http://info.ki.se/ki>
Public Release: 16-Oct-2009
'Spaghetti' scaffolding could help grow skin in labs <http://www.eurekalert.org/pub_releases/2009-10/babs-sc101609.php>
Scientists are developing new scaffolding technology which could be used to grow tissues such as skin, nerves and cartilage using 3D spaghetti-like structures. Their research is highlighted in the latest issue of Business, the quarterly highlights magazine of the Biotechnology and Biological Sciences Research Council.
Contact: Tracey Jewitt
press.office@bbsrc.ac.uk <mailto:press.office@bbsrc.ac.uk>
01-793-414-694
Biotechnology and Biological Sciences Research Council <http://www.bbsrc.ac.uk/>
Public Release: 16-Oct-2009
Super sticky barnacle glue cures like blood clots <http://www.eurekalert.org/pub_releases/2009-10/tcob-ssb100709.php>
Barnacles are a major problem for the shipping industry. Working out how they stick to boat hulls is of major economic importance. On Oct. 16, 2009, Dan Rittschof from Duke University publishes his amazing discovery that barnacle glue cures in the same way that blood clots. "Barnacle glue polymerization is a specialized form of wound healing," says Rittschof.
Contact: Kathryn Knight
kathryn@biologists.com <mailto:kathryn@biologists.com>
44-122-342-5525
The Company of Biologists <http://www.biologists.com/>
Public Release: 15-Oct-2009
Bug barcode readers hold out promise of universal vaccines <http://www.bbsrc.ac.uk/media/releases/2009/091015_bug_barcode_readers_promise_universal_vaccines.html>
Veterinary scientists have made a discovery that promises to deliver a new approach to fast development of cheap vaccines that are effective in all mammals -- not just humans or another particular species.
Contact: Tracey Jewitt
press.office@bbsrc.ac.uk <mailto:press.office@bbsrc.ac.uk>
01-793-414-694
Biotechnology and Biological Sciences Research Council <http://www.bbsrc.ac.uk/>
Public Release: 15-Oct-2009
Gene mutation may reveal clues for treating lung diseases <http://mednews.wustl.edu/news/page/normal/14880.html>
A genetic mutation found in four children born with multiple abnormalities may provide insight into potential treatments for newborn lung distress and chronic obstructive pulmonary disease.
Contact: Beth Miller
millerbe@wustl.edu <mailto:millerbe@wustl.edu>
314-286-0119
Washington University School of Medicine <http://www.medicine.wustl.edu/>
Public Release: 15-Oct-2009
Xenotropic murine leukemia virus-related virus may not be associated with human prostate cancer <http://www.eurekalert.org/pub_releases/2009-10/bc-xml101409.php>
The xenotropic murine leukemia virus-related virus which has previously been linked to prostate cancer has been found to have a dramatically lower prevalence among German prostate cancer patients, if any. Contrary to some reports, which have found XMRV in 40 percent of cases in patients in the US with familial prostate cancer, research published today in BioMed Central's open access journal Retrovirology has found no link between the two conditions in a large study of German prostate cancer patients.
Contact: Charlotte Webber
charlotte.webber@biomedcentral.com <mailto:charlotte.webber@biomedcentral.com>
44-020-319-22129
BioMed Central <http://www.biomedcentral.com/>
Public Release: 15-Oct-2009
Researchers identify promising therapeutic target for central nervous system injuries <http://www.eurekalert.org/pub_releases/2009-10/hms-rip101209.php>
Researchers have identified a promising therapeutic target for central nervous system injuries. Following such an injury, scar tissue releases molecules that keep neurons from passing, so they cannot restore motor and sensory function. Researchers have identified where these inhibitory molecules bind to the surface of neurons, exposing a novel therapeutic target.
Contact: Alyssa Kneller
communications@hms.harvard.edu <mailto:communications@hms.harvard.edu>
617-432-0442
Harvard Medical School <http://hms.harvard.edu/>
Public Release: 15-Oct-2009
Discovery of enzyme structure points way to creating less toxic anti-HIV drugs <http://www.eurekalert.org/pub_releases/2009-10/uota-doe101209.php>
By discovering the atomic structure of a key human enzyme, researchers at the University of Texas at Austin have pointed the way toward designing anti-HIV drugs with far less toxic side effects.
Contact: Whitney Yin
whitney.yin@mail.utexas.edu <mailto:whitney.yin@mail.utexas.edu>
512-471-5583
University of Texas at Austin <http://www.utexas.edu/>
Source - Science Daily:
Please note: Due to the format restrictions of Science Daily articles, you must click on the URL (web address) below the article summary, rather than the article title.
Skin Cells May Provide Early Warning For Cancer Risk Elsewhere In Body <http://www.sciencedaily.com/releases/2009/10/091015163555.htm>
October 16, 2009 — If susceptibility to cancer is the result of inherited genetic mutations, then DNA in all the body's cells should have these mutations. A cell biologist argues that, since skin cells are easy to ...
http://www.sciencedaily.com/releases/2009/10/091015163555.htm <http://www.sciencedaily.com/releases/2009/10/091015163555.htm>
Promising Therapeutic Target For Central Nervous System Injuries Identified <http://www.sciencedaily.com/releases/2009/10/091015141458.htm>
October 16, 2009 — Researchers have identified a promising therapeutic target for central nervous system injuries. Following such an injury, scar tissue releases molecules that keep neurons from passing, so they cannot ...
http://www.sciencedaily.com/releases/2009/10/091015141458.htm <http://www.sciencedaily.com/releases/2009/10/091015141458.htm>
Skin's Pigment Cells Can Be Formed From Completely Different Cells Than Previously Thought <http://www.sciencedaily.com/releases/2009/10/091016121825.htm>
October 16, 2009 — The skin's pigment cells can be formed from completely different cells than has hitherto been thought, a new study from Sweden shows. The results also mean the discovery of a new kind of stem ...
http://www.sciencedaily.com/releases/2009/10/091016121825.htm <http://www.sciencedaily.com/releases/2009/10/091016121825.htm>
Some Color Shades Offer Better Protection Against Sun’s Ultraviolet Rays <http://www.sciencedaily.com/releases/2009/10/091014130708.htm>
October 15, 2009 — Economy-minded consumers who want protection from the sun's harmful ultraviolet rays -- but rather not pay premium prices for sun-protective clothing -- should think blue and red, rather than yellow. ...
http://www.sciencedaily.com/releases/2009/10/091014130708.htm <http://www.sciencedaily.com/releases/2009/10/091014130708.htm>
Which Is Promising As Therapeutic Targets In Patients With Biliary Tract Cancer? EGFR Or HER2? <http://www.sciencedaily.com/releases/2009/10/091016093916.htm>
October 16, 2009 — A research team from Germany analyzed the pathogenetic role and potential clinical usefulness of the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2) in ...
http://www.sciencedaily.com/releases/2009/10/091016093916.htm <http://www.sciencedaily.com/releases/2009/10/091016093916.htm>
Scientists Remove Amyloid Plaques From Brains Of Live Animals With Alzheimer's Disease <http://www.sciencedaily.com/releases/2009/10/091015091602.htm>
October 15, 2009 — A breakthrough discovery in mice may lead to a new treatment for Alzheimer's disease that actually removes amyloid plaques -- considered a hallmark of the disease -- from patients' brains. This ...
http://www.sciencedaily.com/releases/2009/10/091015091602.htm <http://www.sciencedaily.com/releases/2009/10/091015091602.htm>
Loss Of Tumor-suppressor And DNA-maintenance Proteins Causes Tissue Demise <http://www.sciencedaily.com/releases/2009/10/091015171453.htm>
October 15, 2009 — A new study demonstrates that loss of the tumor-suppressor protein p53, coupled with elimination of the DNA-maintenance protein ATR, severely disrupts tissue maintenance in mice. As a result, tissues ...
http://www.sciencedaily.com/releases/2009/10/091015171453.htm <http://www.sciencedaily.com/releases/2009/10/091015171453.htm>
Stem Cells Offer New Hope For Kidney Disease Patients <http://www.sciencedaily.com/releases/2009/10/091015171451.htm>
October 15, 2009 — Several cell-based therapy approaches could provide new treatments for patients with Alport syndrome, according to a new ...
http://www.sciencedaily.com/releases/2009/10/091015171451.htm <http://www.sciencedaily.com/releases/2009/10/091015171451.htm>
Ultra-low Power Actuator Suitable For In-vivo Biomedical Applications <http://www.sciencedaily.com/releases/2009/10/091006104502.htm>
October 14, 2009 — Researchers have developed an actuator that runs on ultra-low power and that is watertight. This innovative combination of characteristics makes the actuator especially suited for use in in-vivo ...
http://www.sciencedaily.com/releases/2009/10/091006104502.htm <http://www.sciencedaily.com/releases/2009/10/091006104502.htm>
Source - Health Day:
Health Highlights: Oct. 16, 2009 <http://www.healthday.com/Article.asp?AID=632063>
- FDA Approves Cervarix Vaccine
- Placebo Effect Detected in Spinal Cord
- Marijuana Used by Nearly 4 Percent of Adults Worldwide: Study
- Special Bracelets Don't Help Arthritis Patients
Warnings issued to 17 centers for lax reporting of procedure-related adverse events.
Docs May Be Overdoing Some Invasive Procedures <http://www.healthday.com/Article.asp?AID=631948>
For certain patients with renal artery stenosis, medication may be enough, researchers say
Clinical Trials Update: Oct. 16, 2009 <http://www.healthday.com/Article.asp?AID=632064>
- Healthy Volunteers (Ages 18+)
- Alzheimer's Disease
- GERD (Acid Reflux)
That idea is not so far-fetched, say scientists who now have possible targets for therapy
Source - Yahoo Biotech News:
Targacept hits annual high on depression drug data <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/ap/091016/us_targacept_depression_drug.html?.v=1> - AP - Fri 10:57 am ET
Shares of Targacept Inc. surged Friday after the company provided full results from a successful mid-stage study of its depression drug candidate TC-5214.
Adipose-Derived Stem and Regenerative Cells Show Potential in First-in-Man Treatment of Stress Urinary Incontinence <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/bw/091015/20091015006463.html?.v=1> - Business Wire - Thu 9:59 pm ET
SAN DIEGO----Cytori was informed that stem and regenerative cells from a patient’s own fat tissue were used to treat stress urinary incontinence as part of an investigator-initiated five patient pilot study in Japan.
China's Swine Flu Darling Is No One Trick Pony <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/indie/091014/2428_id.html?.v=1> - Indie Research - Wed Oct 14
Beijing-based vaccine company Sinovac Biotech has, like many of its peers, experienced its share of pops and drops riding waves of demand on the global epidemic rollercoaster.
Source - Google Health News:
Japanese NIH Research Reaffirms and Expands Pandemic Flu Protection by Ampligen(R) <http://www.google.com/url?sa=X&q=http://www.globenewswire.com/newsroom/news.html%3Fd%3D175541&ct=ga&cd=npFO5fNrwMI&usg=AFQjCNEbfCq0Y1M8jugw8hh6VzWj55ChbA>
GlobeNewsWire (press release)
Dr. Hasegawa provided an overview of intranasal pandemic flu vaccine ( H5N1) and nasal immunity mechanisms. The new data consist of both expanded clinical ...
Sales of GlaxoSmithKline's Relenza Likely to Increase During the A/H1N1 2009 <http://www.google.com/url?sa=X&q=http://www.prnewswire.com/news-releases/sales-of-glaxosmithklines-relenza-likely-to-increase-during-the-ah1n1-2009-pandemic-as-tamiflu-resistant-strains-of-the-virus-spread-64352097.html&ct=ga&cd=npFO5fNrwMI&am>
PR Newswire (press release)
"Relenza did not enjoy the success seen by Tamiflu during the H5N1 influenza scare, also known as the avian flu, mostly because it is an inhalable product, ...
Gene Therapy Method Slows Tumor Growth in Mice <http://www.google.com/url?sa=X&q=http://media-newswire.com/release_1102875.html&ct=ga&cd=7Z96XvX-d_k&usg=AFQjCNFY3pcPKtcN76LH70FK6OBAswUleg>
Media Newswire (press release)
... cells in the tumor tissue to die and slowed tumor growth significantly. The results of this study appeared online October 9, 2009, in Cancer Gene Therapy.
AMT's DMD treatment gains orphan status in Europe <http://www.google.com/url?sa=X&q=http://www.reuters.com/article/rbssHealthcareNews/idUSLD54527920091013&ct=ga&cd=_SjXUD9piOI&usg=AFQjCNFIdYsgsw1fwk5HgHiGtZUnd0FE5w>
Reuters
AS) said on Tuesday its gene therapy treatment for Duchenne muscular dystrophy has been granted orphan drug designation by the European Medicines Agency ...
A Gene Tweak Could Keep Heart Young <http://www.google.com/url?sa=X&q=http://www.usnews.com/articles/health/healthday/2009/10/12/a-gene-tweak-could-keep-heart-young.html&ct=ga&cd=_SjXUD9piOI&usg=AFQjCNFZFmZQQrWgBvkvEW6YoT4M6GCAnQ>
U.S. News & World Report
The gene plays an important role in both the aging and proliferation of cells, and research is aimed at developing gene therapy not only for heart disease ...
China is in the lead for a new cancer alternative treatment <http://www.google.com/url?sa=X&q=http://www.bestsyndication.com/%3Fq%3D20091014_china_cancer_treatments.htm&ct=ga&cd=c2zfzPGeQBM&usg=AFQjCNEMlNxsy8rlW6PBN28KWbitoRQabQ>
Best Syndication
Since the arrival of the world's first government-approved gene therapy for cancer drug in 2003, China has been propelled to the front of the pack in the ...
Long-term monkey tests back Oxford's gene therapy <http://www.google.com/url?sa=X&q=http://www.reuters.com/article/scienceNews/idUSTRE59D4DL20091014&ct=ga&cd=c2zfzPGeQBM&usg=AFQjCNHpx42lcOZSMwaZPbJhGivLVAMPNg>
Reuters
LONDON (Reuters) - Long-term tests on monkeys using Oxford BioMedica's gene therapy ProSavin suggest it can treat Parkinson's disease without causing the ...
Source - Medical News Today:
Inovio Biomedical Announces Initiation Of HIV Clinical Trial For DNA Vaccine Delivered Using Electroporation <http://www.medicalnewstoday.com/articles/167685.php>
Inovio Biomedical Corporation (NYSE Amex: INO), a leader in DNA vaccine design, development and delivery, and the HIV <http://www.medicalnewstoday.com/articles/17131.php> Vaccine Trials Network (HVTN) announced today the initiation of a phase I clinical study of Inovio's PENNVAX™-B preventive DNA vaccine delivered using its proprietary electroporation technology. The multi-center study will be conducted at several HVTN clinical sites under a protocol designated HVTN-080. The study will enroll healthy volunteers to assess the safety of and immune responses to this DNA-based vaccine delivered via in vivo electroporation. Inovio previously reported data from non-human primates demonstrating up to a 100-fold enhancement in immune responses resulting from the vaccine when delivered via in vivo electroporation compared to syringe injection without electroporation. PENNVAX™-B is currently in a clinical study, being conducted under the HVTN-070 protocol by the same group of collaborators, to test safety and immunogenicity of the vaccine delivered via intramuscular syringe injection without electroporation. The HVTN-080 follow-on study is sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), an NIH agency.
http://www.medicalnewstoday.com/articles/167685.php <http://www.medicalnewstoday.com/articles/167685.php>
Trialing Major Weight Loss For Type 2 Diabetes In The Overweight <http://www.medicalnewstoday.com/articles/167532.php>
In the first trial of its kind in the world, researchers at Monash University's Centre for Obesity Research and Education (CORE) will examine the benefits of a gastric banding procedure on overweight people with Type 2 diabetes <http://www.medicalnewstoday.com/info/diabetes/whatisdiabetes.php> . Lead investigator Professor Paul O'Brien said until now gastric banding surgery was reserved for people who were obese - with a Body Mass Index (BMI) rating greater than 30.
http://www.medicalnewstoday.com/articles/167532.php <http://www.medicalnewstoday.com/articles/167532.php>
Medical Imaging Identifies Severe Case Of H1N1 And May Help Researchers Understand The Pathogenesis Of The Virus <http://www.medicalnewstoday.com/articles/167450.php>
Researchers at the National Institutes of Health (NIH) have found that imaging can now be used as a tool for identifying severe cases of H1N1 <http://www.medicalnewstoday.com/articles/147720.php> and may play a key role in understanding the pathogenesis of the virus, possibly leading to earlier diagnoses of severe cases in the future, according to a study published online today in the American Journal of Roentgenology. The study will be published in the December issue of AJR. Imaging revealed a severe case of H1N1 after a patient had tested negative using a nasal swab rapid antigen test. Radiography (standard X -ray) showed peripheral lung opacities, and computed tomography (CT) revealed peripheral ground-glass opacities. Both findings raised suspicion of H1N1 and reports revealed that the patient later died from a severe case of H1N1.
http://www.medicalnewstoday.com/articles/167450.php <http://www.medicalnewstoday.com/articles/167450.php>
A New Scan For Lung Diseases <http://www.medicalnewstoday.com/articles/167376.php>
People with chronic lung disease and asthma <http://www.medicalnewstoday.com/info/asthma/what-is-asthma.php> could soon be offered better treatment thanks to a new type of Magnetic Resonance Imaging (MRI) scan being pioneered at The University of Nottingham. A purpose-built MRI research unit has been established to study a range of respiratory diseases. The unit is based at the Queens Medical Centre and will allow doctors to virtually 'see inside' the lungs of patients using a new, specifically-adapted MRI scanner.
http://www.medicalnewstoday.com/articles/167376.php <http://www.medicalnewstoday.com/articles/167376.php>
-
Source - MIT's Technology Review:
Making Heart Muscle <http://www.technologyreview.com/biomedicine/23746/>
http://www.technologyreview.com/biomedicine/23746/ <http://www.technologyreview.com/biomedicine/23746/>
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