Source - EurekAlert – Biology
Public Release: 2-Jul-2009
Study identifies how tamoxifen stimulates uterine cell growth and cancer
University of California - San Francisco researchers have identified a new "feed-forward" pathway linking estrogen receptors in the membrane of the uterus to a process that increases local estrogen levels and promotes cell growth.
Contact: Kristen Bole
kbole@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
Public Release: 2-Jul-2009
Ben-Gurion U. researchers reveal connection between cancer and human evolution
Researchers at Ben-Gurion University of the Negev have discovered that gene mutations that once helped humans survive may increase the possibility for diseases, including cancer. The findings were recently the cover story in the journal Genome Research.
Contact: Andrew Lavin
andrewlavin@alavin.com
212-290-9540
American Associates, Ben-Gurion University of the Negev
Public Release: 2-Jul-2009
UCLA scientists find molecular differences between embryonic stem cells and reprogrammed skin cells
UCLA researchers have found that embryonic stem cells and skin cells reprogrammed into embryonic-like cells have inherent molecular differences, demonstrating for the first time that the two cell types are clearly distinguishable from one another.
Contact: Kim Irwin
kirwin@mednet.ucla.edu
310-206-2805
University of California - Los Angeles
Public Release: 2-Jul-2009
Gene's novel role may provide key to treating liver and neurodegenerative diseases
Singapore scientists have made a novel discovery about how gene, "Fas-apoptosis inhibitory molecule", protects both immune and liver cells from programmed cell death. Their research is published in Cell Death and Differentiation.
Contact: Cathy Yarbrough
sciencematter@yahoo.com
858-243-1814
Agency for Science, Technology and Research (A*STAR), Singapore
Public Release: 2-Jul-2009
'Jumping gene' diminishes the effect of a new type 2 diabetes risk gene
Research has identified a new gene associated with diabetes, together with a mechanism that makes obese mice less susceptible to diabetes. A genomic fragment that occurs naturally in some mouse strains diminishes the activity of the risk gene Zfp69. The researchers also found that the corresponding human gene (ZNF642) is especially active in overweight individuals with diabetes. The results of the study are published July 3 in the open-access journal PLoS Genetics.
Contact: Catriona Silvey
csilvey@plos.org
Public Library of Science
Public Release: 2-Jul-2009
Research reveals what drives lung cancer's spread
A new study by researchers at Memorial Sloan-Kettering Cancer Center reveals the genetic underpinnings of what causes lung cancer to quickly metastasize, or spread, to the brain and the bone -- the two most prominent sites of lung cancer relapse. The study will be published online in the journal Cell on July 2.
Contact: Esther Napolitano
napolite@mskcc.org
646-227-3139
Memorial Sloan-Kettering Cancer Center
Public Release: 2-Jul-2009
New targeted therapy finds and eliminates deadly leukemia stem cells
New research describes a molecular tool that shows great promise as a therapeutic for human acute myeloid leukemia, a notoriously treatment-resistant blood cancer. The study, published by Cell Press in the July 2 issue of the journal Cell Stem Cell, describes exciting preclinical studies in which a new therapeutic approach selectively attacks human cancer cells grown in the lab and in animal models of leukemia.
Contact: Cathleen Genova
cgenova@cell.com
617-397-2802
Cell Press
Source - Science Daily:
Please note: Due to the format restrictions of Science Daily articles, you must click on the URL (web address) below the article summary, rather than the article title.
Predicting The Return Of Prostate Cancer: New Study Betters The Odds Of Success
July 3, 2009 — Cancer experts say a study tracking 774 prostate cancer patients for a median of eight years has shown that a three-way combination of measurements has the best chance yet of predicting disease ...
http://www.sciencedaily.com/releases/2009/07/090702090603.htm
Computer Scientists Develop Model For Studying Arrangements Of Tissue Networks By Cell Division
July 3, 2009 — Computer scientists have developed a framework for studying the arrangement of tissue networks created by cell division across a diverse set of organisms, including fruit flies, tadpoles and ...
http://www.sciencedaily.com/releases/2009/06/090617105048.htm
Why H1N1 Flu Spreads Inefficiently
July 3, 2009 — Scientists have found a genetic explanation for why the new H1N1 "swine flu" virus has spread from person to person less effectively than other flu viruses. But researchers say the new strain bears ...
http://www.sciencedaily.com/releases/2009/07/090702140849.htm
Lifespan Of HIV-infected Cells Might Be Shorter Than Previously Believed
July 3, 2009 — Researchers have used mathematical models to demonstrate that cells infected with HIV could die sooner than was thought until now. If infected cells have a shorter lifespan then this increases the ...
http://www.sciencedaily.com/releases/2009/06/090630163326.htm
Doubts Cast On Credibility Of Some Published Clinical Trials
July 3, 2009 — Randomized controlled trials are considered the "gold standard" research method for assessing new medical treatments. But new research shows that the design of a remarkable 93 percent of 2235 ...
http://www.sciencedaily.com/releases/2009/07/090702184146.htm
Virus-gene Therapy Combination Against Melanoma Under Testing
July 2, 2009 — Researchers are injecting a modified herpes virus into melanoma tumors, hoping to kill the cancer cells while also bolstering the body's immune defenses against the ...
http://www.sciencedaily.com/releases/2009/07/090701183003.htm
Possibility Of Vaccine For Ear Infections
July 2, 2009 — Otitis media, more commonly known as an ear infection, is the most frequently diagnosed illness in children less than 15 years of age in the United States and is the primary cause for emergency room ...
http://www.sciencedaily.com/releases/2009/06/090630220515.htm
Alzheimer's Symptoms Reversed: Blood Stem Cell Growth Factor Reverses Memory Decline In Mice
July 2, 2009 — A human growth factor that stimulates blood stem cells to proliferate in bone marrow reverses memory impairment in mice genetically altered to develop Alzheimer's disease, a new study ...
http://www.sciencedaily.com/releases/2009/07/090701160557.htm
Protein In The Envelope Enclosing The Cell Nucleus: New Piece Of The Puzzle In Research On Cancer And Stem Cells?
July 2, 2009 — Scientists have discovered a new protein in the inner membrane of the cell nucleus. This protein may play an important role in cell division and now provides a new piece of the puzzle to study in ...
http://www.sciencedaily.com/releases/2009/06/090617080406.htm
Analysis Of Drug-eluting Stents Data Demonstrates Safety, Efficacy In On-and-off-label Use
July 2, 2009 — The Cardiovascular Research Foundation has announced the results of the largest meta-analysis to date comparing mortality rates for drug-eluting stents versus bare metal stents. The study also ...
http://www.sciencedaily.com/releases/2009/06/090616122117.htm
New Enemy For Tumor-suppressor P53 Identified
July 1, 2009 — Researchers have identified a protein that marks the tumor suppressor p53 for destruction, providing a potential new avenue for restoring p53 in cancer ...
http://www.sciencedaily.com/releases/2009/06/090626190937.htm
Uncovering How Cells Cover Gaps In Wound Healing And Embryonic Development
July 1, 2009 — Researchers have come a step closer to understanding how cells close gaps not only during embryonic development but also during wound healing. Their study uncovers a fundamental misconception in the ...
http://www.sciencedaily.com/releases/2009/06/090626084427.htm
Hungry Cells: Tumor Metabolism Discovery Opens New Detection And Treatment Possibilities For Rare Form Of Colon Cancer
July 1, 2009 — People who suffer from Peutz-Jeghers syndrome, a rare inherited cancer syndrome, develop gastrointestinal polyps and are predisposed to colon cancer and other tumor types. Carefully tracing the ...
http://www.sciencedaily.com/releases/2009/06/090615171521.htm
X-rays For Early Alzheimer's Disease Detection
July 1, 2009 — Researchers have demonstrated a new, highly detailed x-ray imaging technique that could be developed into a method for early diagnosis of Alzheimer's disease. The technique has previously been used ...
http://www.sciencedaily.com/releases/2009/06/090616103313.htm
Cell Transplantation And Cardiac Repair
July 1, 2009 — Two separate studies on cardiac repair by cell transplantation have found, respectively, that the best way to deliver autologous bone-marrow mononuclear cells to the heart following a myocardial ...
http://www.sciencedaily.com/releases/2009/07/090701122714.htm
Biomarker That Safely Monitors Tumor Response To New Brain Cancer Treatment
July 1, 2009 — A specific biomarker, a protein released by dying tumor cells, has been identified as an effective tool in an animal model to gauge the response to a novel gene therapy treatment for glioblastoma ...
http://www.sciencedaily.com/releases/2009/07/090701082714.htm
Source - Health Day:
Health Highlights: July 2, 2009
- Many More Kids Vaccinated For Hepatitis A
- TB Vaccine May Be Fatal for Infants With HIV
- Colon Cancer Study Is Stopped
- U.S. Government to Seek Answers to Health-Care Questions
Losing a partner through divorce or death in middle age may triple the risk, study shows
If 2 Painkillers Are Banned, What Next?
Other options, available and in the pipeline, could plug a Percocet-Vicodin gap, experts say
New Drug Could Work Against Leukemia
Researchers see promise for treatment of AML and other cancers
Clinical Trials Update: July 2, 2009
- Rhinitis, Allergic, Perennial
- Depression
- Diabetic Neuropathy
- ADHD (Attention Deficit Hyperactivity Disorder)
- Menopause and Osteoporosis Prevention
- Healthy Volunteers (Ages 18-65)
Eight of 10 states with highest number of obese adults are in the South, report says
Clinical Trials Update: July 1, 2009
- Low Back Pain
- COPD (Chronic Obstructive Pulmonary Disease)
- Atrial Fibrillation
- Menopause
- Migraine and Cluster Headaches
- Diabetes Mellitus, Type 2
- Chronic Obstructive Pulmonary Disease (COPD)
- Glioblastoma multiforme
- Fibromyalgia
- Type 2 Diabetes
- Depression - Adult
- Depression
Source - Yahoo Biotech News:
Genentech says Lucentis met goal in clinical trial
Genentech Inc. said Thursday its macular degeneration drug Lucentis met its goal in a late stage trial, improving the vision of patients with macular edema due to branch retinal vein occlusion.
Johnson & Johnson pays $1B for Elan stake
Johnson & Johnson, making a big jump into the risky but potentially lucrative field of Alzheimer's disease, is taking a major stake in Irish biopharmaceutical company Elan Corp., investing up to $1.5 billion initially.
Source - Google Health News:
Sinovac obtains revised approvals for pandemic influenza vaccine
Trading Markets (press release) - Los Angeles,CA,USA
This vaccine will be sold under the Panflu brand, which has in the past also referred to Sinovac's vaccine against the pandemic influenza strain, H5N1. ...
Strides seen on swine flu vaccine
San Diego Union Tribune - San Diego,CA,USA
In 2004, it had a SARS vaccine ready for human tests, and in 2005 it began studying a vaccine for H5N1 avian flu virus. The company lost $36.9 million last ...
Novavax in multi-million Spanish deal on vaccines
Town Hall - Washington,DC,USA
Vaccine developer Novavax Inc. signs a deal with Spain's health ministry to license its genetically engineered technology to produce pandemic and seasonal ...
Medicago's vaccine candidate against novel influenza A (H1N1 ...
Canada NewsWire (press release) - Toronto,Ontario,Canada
"With our lead H5N1 vaccine candidate expected to commence human trials in the third quarter of this year, we look forward to delivering additional ...
Novel Gene Therapy for Brain Tumor Nears Clinical Trial Rat study ...
Modern Medicine - Woodcliff Lake,NJ,USA
THURSDAY, July 2 (HealthDay News) -- A novel gene therapy for glioblastoma multiforme utilizing a combination of adenoviral vectors and the drug ganciclovir ...
Virus-gene Therapy Combination Against Melanoma Under Testing
Science Daily (press release) - USA
ScienceDaily (July 1, 2009) — Researchers at the Moores UCSD Cancer Center are injecting a modified herpes virus into melanoma tumors, hoping to kill the ...
Medtronics pumps $2.5M into NanoCor Therapeutics
Bizjournals.com - Charlotte,NC,USA
NanoCor said on Tuesday that the additional investment will be used to develop and commercialize its gene therapy. Medtronic has agreed to invest additional ...
Gene Therapy for Brain Cancer
Ivanhoe - Winter Park,FL,USA
The two-pronged gene therapy was devised by scientists at the Cedars-Sinai Board of Governors Gene Therapeutics Research Institute. It uses a harmless, ...
Source - Medical News Today:
Undiagnosed Celiac Disease More Common Today Than 50 Years Ago Say US Researchers
US researchers said that undiagnosed cases of celiac disease, where the immune system has a strong adverse reaction to the protein found in wheat and other grains, appear to have increased dramatically in the last 50 years. They also found, over a 45 year follow up, that people with undiagnosed celiac disease have a nearly four-fold increased risk of premature death from any cause. The study was led by researchers at the Mayo Clinic in Rochester, Minnesota, and appears online in the July issue of the journal Gastroenterology
http://www.medicalnewstoday.com/articles/156401.php
FDA Panel Votes To Restrict Acetaminophen
An advisory committee to the US Food and Drug Administration (FDA) voted on Tuesday to recommend new restrictions on the popular pain relief drug acetaminophen (known in many other countries as paracetamol), which is found in many US top selling over the counter medications such as Tylenol, aspirin-free Anacin, Excedrin
http://www.medicalnewstoday.com/articles/156256.php
Alzheimer's Research Yields Potential Drug Target
Scientists at UC Santa Barbara and several other institutions have found laboratory evidence that a cluster of peptides may be the toxic agent in Alzheimer's disease. Scientists say the discovery may lead to new drugs for the disease. In an article published this week in Nature Chemistry, the researchers explain the process in which the toxic Amyloid Beta 42 peptides aggregate, and outline the new technology they use to study these peptides. The findings come out of the laboratory of Michael T. Bowers, professor of chemistry and biochemistry at UCSB.
http://www.medicalnewstoday.com/articles/156186.php
Pfizer Discontinues Phase 3 Trial Of Sutent(R) In Metastatic Colorectal Cancer
Pfizer Inc announced the discontinuation of the SUN 1122 Phase 3 trial that evaluated Sutent
http://www.medicalnewstoday.com/articles/156079.php
Source - MIT's Technology Review:
A Limb Regeneration Mystery Solved
http://www.technologyreview.com/biomedicine/22955/
Can Aging Be Solved?
http://www.technologyreview.com/biomedicine/22954/
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.