Since August, 2005, this news digest has been a complimentary service of GBP Capital, a private equity firm investing in early to mid-stage life science companies. See www.gbpcap.com. The digest is published two to four days a week. If you have colleagues who would be interested in receiving this digest by email, they can be added to the list at: http://www.gbpcap.com/ <http://www.gbpcap.com/> . Also, the complete history of the entire content of all news articles in our digests since August, 2005 is searchable with Google's enterprise search engine at the same site.
Source - EurekAlert – Biology
Public Release: 28-May-2009
Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue <http://www.buffalo.edu/news/10132>
University at Buffalo researchers have demonstrated for the first time that injecting adult bone marrow stem cells into skeletal muscle can repair cardiac tissue, reversing heart failure.
Contact: Lois Baker
ljbaker@buffalo.edu <mailto:ljbaker@buffalo.edu>
716-645-5000 x1417
University at Buffalo <http://www.buffalo.edu>
Public Release: 28-May-2009
Scientists develop a new HIV microbicide -- and a way to mass produce it in plants <http://www.eurekalert.org/pub_releases/2009-05/foas-sda052809.php>
In what could be a major pharmaceutical breakthrough, research published online in the FASEB Journal describes how scientists from St George's, University of London have devised a one-two punch to stop HIV. First the report describes a new protein that can kill the virus when used as a microbicide. Then the report shows how it might be possible to manufacture this protein in quantities large enough to make it affordable for people in developing countries.
Contact: Cody Mooneyhan
cmooneyhan@faseb.org <mailto:cmooneyhan@faseb.org>
301-634-7104
Federation of American Societies for Experimental Biology <http://www.faseb.org>
Public Release: 28-May-2009
Study may aid efforts to prevent uncontrolled cell division in cancer <http://www.eurekalert.org/pub_releases/2009-05/uoc--sma052709.php>
Researchers from the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine have uncovered a remarkable property of the contractile ring, a structure required for cell division. Understanding how the contractile ring works to divide the cell may facilitate development of therapies to prevent uncontrolled cell division in cancer.
Contact: Steve Benowitz
sbenowitz@ucsd.edu <mailto:sbenowitz@ucsd.edu>
619-543-6163
University of California - San Diego <http://www.ucsd.edu>
Public Release: 28-May-2009
The vulnerable cancer cell <http://www.hhmi.org/news/synlethal20090529.html>
Howard Hughes Medical Institute researchers have identified many potential new drug targets for cancers long deemed "untouchable" due to the type of genetic mutation they contain. These studies are beginning to reveal new ways of attacking cancer by targeting a largely hidden network of normal genes that cancer cells rely on for survival.
Contact: Jim Keeley
keeleyj@hhmi.org <mailto:keeleyj@hhmi.org>
301-215-8858
Howard Hughes Medical Institute <http://www.hhmi.org>
Public Release: 28-May-2009
Hitting cancer where it hurts <http://www.eurekalert.org/pub_releases/2009-05/cp-hcw052209.php>
Two studies in the May 29 issue of Cell, a Cell Press publication, have taken advantage of new technological advances to search for and find previously unknown weaknesses in a hard to treat form of cancer. The discoveries lend new hope in the fight again tumors that are today considered "undruggable."
Contact: Cathleen Genova
cgenova@cell.com <mailto:cgenova@cell.com>
617-397-2802
Cell Press <http://www.cellpress.com>
Public Release: 27-May-2009
First comprehensive guidelines for managing medullary thyroid carcinoma published in Thyroid journal <http://www.eurekalert.org/pub_releases/2009-05/mali-fcg052709.php>
New guidelines designed to standardize and optimize the diagnosis, treatment, and monitoring of patients with medullary thyroid carcinoma , an uncommon and challenging form of thyroid cancer, have been developed by the American Thyroid Association and published online ahead of print in Thyroid, a peer-reviewed journal published by Mary Ann Liebert Inc. The guidelines are available free online.
Contact: Vicki Cohn
vcohn@liebertpub.com <mailto:vcohn@liebertpub.com>
914-740-2156
Mary Ann Liebert, Inc./Genetic Engineering News <http://www.liebertpub.com>
Public Release: 26-May-2009
In a rare disorder, a familiar protein disrupts gene function <http://www.eurekalert.org/pub_releases/2009-05/plos-iar052109.php>
In this week's PLoS Biology, an international team of scientists studying a rare genetic disease has discovered that a bundle of proteins already known to be important for keeping chromosomes together also plays an important role in regulating gene expression in humans. In addition to shedding light on the biological roles of these proteins, the research may lead to the development of better diagnostic tools for Cornelia de Lange syndrome, a multisystem developmental disease.
Contact: Sally Hubbard
press@plos.org <mailto:press@plos.org>
Public Library of Science <http://www.plos.org>
Public Release: 26-May-2009
What is the function of lymph nodes? <http://www.eurekalert.org/pub_releases/2009-05/plos-wit052109.php>
A new paper, published in this week's issue of PLoS Biology, suggests that lymph nodes are not essential in the mouse in marshaling T-cells (a main immune foot soldier) to respond to a breach of the skin barrier. This result is both surprising in itself, and suggests a novel function for the liver as an alternate site for T-cell activation.
Contact: Sally Hubbard
press@plos.org <mailto:press@plos.org>
Public Library of Science <http://www.plos.org>
Public Release: 26-May-2009
Viruses are sneakier than we thought <http://www.eurekalert.org/pub_releases/2009-05/plos-vas052109.php>
Of central importance for viruses is the ability to commandeer cellular gene expression machinery. Several human herpes viruses put the breaks on normal cellular gene expression to divert the associated enzymes and resources towards their own viral genes. Kaposi's sarcoma-associated herpes virus, which causes several AIDS-associated cancers, has now been shown to do this in an unexpected way, using a process that is normally protective, called polyadenylation.
Contact: Sally Hubbard
press@plos.org <mailto:press@plos.org>
Public Library of Science <http://www.plos.org>
Public Release: 26-May-2009
Meet the complete mouse -- whole mouse genome sequence published <http://www.eurekalert.org/pub_releases/2009-05/plos-mtc052109.php>
A new paper, published in this week's issue of PLoS Biology, explores exactly what distinguishes our genome from that of the lab mouse. In the first comprehensive comparison between the genes of mice and humans, scientists from institutions across America, Sweden and the UK reveal that there are more genetic differences between the two species than had been previously thought.
Contact: Sally Hubbard
press@plos.org <mailto:press@plos.org>
Public Library of Science <http://www.plos.org>
Public Release: 26-May-2009
Zebrafish provide a model for cancerous melanoma in humans <http://www.eurekalert.org/pub_releases/2009-05/tcob-zpa051909.php>
In a new study published in Disease Models & Mechanisms, scientists use the zebrafish to gain insight into the influence of known cancer genes on the development and progression of melanoma, an aggressive form of human skin cancer with limited treatment options.
Contact: Sarah Sharpe
sarah.sharpe@biologists.com <mailto:sarah.sharpe@biologists.com>
The Company of Biologists <http://www.biologists.com>
Public Release: 25-May-2009
Nervous system may be culprit in deadly muscle disease <http://www.eurekalert.org/pub_releases/2009-05/uof-nsm052109.php>
Long considered a "muscle" disorder, Pompe disease may have a previously unknown neural component. In mouse models of the disease, University of Florida researchers have discovered that signals from the spinal cord are too weak to reach the diaphragm -- the muscle that controls breathing. The finding suggests that therapies to treat the disease will need to take the central nervous system into account in order to be fully effective.
Contact: John Pastor
jdpastor@ufl.edu <mailto:jdpastor@ufl.edu>
352-273-5815
University of Florida <http://www.ufl.edu>
Public Release: 25-May-2009
Identification of genetic variants affecting age at menopause could help improve fertility treatment <http://www.eurekalert.org/pub_releases/2009-05/esoh-iog052109.php>
For the first time, scientists have been able to identify genetic factors that influence the age at which natural menopause occurs in women. Ms. Lisette Stolk, a researcher from Erasmus MC, Rotterdam, the Netherlands, told the annual conference of the European Society of Human Genetics today that a greater understanding of the factors influencing age at menopause might eventually help to improve the clinical treatment of infertile women.
Contact: Mary Rice
mary@mrcommunication.org <mailto:mary@mrcommunication.org>
European Society of Human Genetics <http://www.eshg.org>
Public Release: 25-May-2009
Scientists find shared genetic link between the dental disease periodontitis and heart attack <http://www.eurekalert.org/pub_releases/2009-05/esoh-sfs052109.php>
The relationship between the dental disease periodontitis and coronary heart disease has been known for several years. Although a genetic link seemed likely, until now its existence was uncertain. Now, for the first time, scientists have discovered a genetic relationship between the two conditions, a researcher told the annual conference of the European Society of Human Genetics today.
Contact: Mary Rice
mary@mrcommunication.org <mailto:mary@mrcommunication.org>
European Society of Human Genetics <http://www.eshg.org>
Public Release: 25-May-2009
Heart saves muscle <http://www.eurekalert.org/pub_releases/2009-05/rup-hsm051809.php>
A heart muscle protein can replace its missing skeletal muscle counterpart to give mice with myopathy a long and active life, show Nowak et al.
Contact: Rita Sullivan
news@rupress.org <mailto:news@rupress.org>
212-327-8603
Rockefeller University Press <http://www.rockefeller.edu/RUPress/>
Source - Science Daily:
Please note: Due to the format restrictions of Science Daily articles, you must click on the URL (web address) below the article summary, rather than the article title.
New Therapy Enlists Immune System To Boost Cure Rate In Childhood Cancer <http://www.sciencedaily.com/releases/2009/05/090527181540.htm>
May 28, 2009 — Scientist have announced encouraging results for an experimental therapy using elements of the body's immune system to improve cure rates for children with neuroblastoma, a challenging cancer of the ...
http://www.sciencedaily.com/releases/2009/05/090527181540.htm
New Cellular Targets For HIV Drug Development <http://www.sciencedaily.com/releases/2009/05/090527181544.htm>
May 28, 2009 — Focusing HIV drug development on immune cells called macrophages could help combat the disease, according to new ...
http://www.sciencedaily.com/releases/2009/05/090527181544.htm
The Vulnerable Cancer Cell: New Studies Reveal Broad, Hidden Network That Lets Tumors Thrive <http://www.sciencedaily.com/releases/2009/05/090528120647.htm>
May 28, 2009 — Researchers have identified many potential new drug targets for cancers long deemed "untouchable" due to the type of genetic mutation they contain. These studies are beginning to reveal new ways of ...
http://www.sciencedaily.com/releases/2009/05/090528120647.htm
Genetic Testing For Breast Or Ovarian Cancer Risk May Be Greatly Underutilized
May 27, 2009 — Although a test for gene mutations known to significantly increase the risk of hereditary breast or ovarian cancer has been available for more than a decade, a new study finds that few women with ...
http://www.sciencedaily.com/releases/2009/05/090521131315.htm
Less-toxic Drug Prolongs Survival In Metastatic Breast Cancer <http://www.sciencedaily.com/releases/2009/05/090526162846.htm>
May 27, 2009 — A less toxic, solvent-free chemotherapy drug more effectively prevents the progression of metastatic breast cancer and has fewer side effects than a commonly used solvent-based drug. Abraxane ...
http://www.sciencedaily.com/releases/2009/05/090526162846.htm
Green Tea Extract Shows Promise In Leukemia Trials <http://www.sciencedaily.com/releases/2009/05/090526163010.htm>
May 27, 2009 — Researchers are reporting positive results in early leukemia clinical trials using the chemical epigallocatechin gallate, an active ingredient in green ...
http://www.sciencedaily.com/releases/2009/05/090526163010.htm
Can We Afford The Cancer Care Of The Future? <http://www.sciencedaily.com/releases/2009/05/090526140751.htm>
May 27, 2009 — When a cancer patient and his or her doctor discuss the value of a treatment option, the conversation usually centers on a consideration of the treatment's medical benefits versus its possible side ...
http://www.sciencedaily.com/releases/2009/05/090526140751.htm
Newly Discovered Mechanism Promotes Blood Clot Formation <http://www.sciencedaily.com/releases/2009/05/090526094300.htm>
May 26, 2009 — Researchers in Australia have discovered an entirely new mechanism that promotes blood clot formation -- a major breakthrough that will impact on treatment and prevention of heart disease and ...
http://www.sciencedaily.com/releases/2009/05/090526094300.htm
Protein Identified As Critical To Insulating The Body's Wiring Could Also Become Treatment Target <http://www.sciencedaily.com/releases/2009/05/090519134826.htm>
May 26, 2009 — A new protein identified as critical to insulating the wiring that connects the brain and body could one day be a treatment target for divergent diseases, from rare ones that lower the pain threshold ...
http://www.sciencedaily.com/releases/2009/05/090519134826.htm
How Viral Infection Can Protect From Type 1 Diabetes <http://www.sciencedaily.com/releases/2009/05/090526171807.htm>
May 26, 2009 — Type 1 diabetes is caused by immune system–mediated destruction of insulin-producing beta-cells in the pancreas. It is known that infection with a virus can induce an immune response that ...
http://www.sciencedaily.com/releases/2009/05/090526171807.htm
New Broad-spectrum Vaccine To Prevent Cervical Cancer Induces Strong Responses In Animals <http://www.sciencedaily.com/releases/2009/05/090526162842.htm>
May 26, 2009 — Mice and rabbits immunized with a multimeric-L2 protein vaccine had robust antibody responses and were protected from infection when exposed to human papillomavirus type 16 four months after ...
http://www.sciencedaily.com/releases/2009/05/090526162842.htm
Activated Stem Cells In Damaged Lungs Could Be First Step Toward Cancer <http://www.sciencedaily.com/releases/2009/05/090526140856.htm>
May 26, 2009 — Stem cells that respond after a severe injury in the lungs of mice may be a source of rapidly dividing cells that lead to lung cancer, according to a new ...
http://www.sciencedaily.com/releases/2009/05/090526140856.htm
Stem Cells Transplanted From Marrow Into Heart May Improve Heart's Performance <http://www.sciencedaily.com/releases/2009/05/090526094616.htm>
May 26, 2009 — Scientists are carrying out clinical tests with patients who have suffered from a severe heart attack. With the implantation of the patient’s stem cells, the heart regenerates thus improving ...
http://www.sciencedaily.com/releases/2009/05/090526094616.htm
Virus Tamed To Destroy Cancer Cells But Leave Healthy Cells Unharmed <http://www.sciencedaily.com/releases/2009/05/090522081217.htm>
May 25, 2009 — Scientists have tamed a virus so that it attacks and destroys cancer cells but does not harm healthy cells. They have determined how to produce replication-competent viruses with key toxicities ...
http://www.sciencedaily.com/releases/2009/05/090522081217.htm
Efficacy Of CT Scans For Chest Pain Diagnosis Validated <http://www.sciencedaily.com/releases/2009/05/090515104219.htm>
May 23, 2009 — The first long-term study following a large number of chest pain patients who are screened with coronary computerized tomographic angiography confirms that the test is a safe, effective way to rule ...
http://www.sciencedaily.com/releases/2009/05/090515104219.htm
Intelligent Life Sciences Search Engine: Grid Browser Understands Technical Terms And Context <http://www.sciencedaily.com/releases/2009/05/090521084719.htm>
May 23, 2009 — A web browser that can understand technical terms in life sciences and automatically find additional resources and services has been developed. It could lead to a new generation of intelligent search ...
http://www.sciencedaily.com/releases/2009/05/090521084719.htm
Source - Health Day:
Health Highlights: May 27, 2009 <http://www.healthday.com/Article.asp?AID=627471>
- Test for Early Alzheimer's Moving Forward: Report
- Minnesota Boy to Undergo Chemotherapy
- Court Rules 'Light' Cigarettes Duped Smokers
Report finds 19.2% drop among men, 11.4% among women in past 15 years.
Drug May Extend Life When Breast Cancer Spreads <http://www.healthday.com/Article.asp?AID=627382>
Study funded by pharmaceutical company finds benefits in Abraxane
Too Much Cola Can Cause Muscle Problems <http://www.healthday.com/Article.asp?AID=627269>
Drop in potassium levels may lead to mild weakness or temporary paralysis, study finds
Hardened Arteries Threaten Obese, Diabetic Youth <http://www.healthday.com/Article.asp?AID=627295>
Ultrasound shows damage tied to rising odds for stroke, heart attack, researchers say
Clinical Trials Update: May 26, 2009 <http://www.healthday.com/Article.asp?AID=627430>
- Constipation
- Depression (Adult and Geriatric)
- Conjunctivitis, Bacterial
- Schizophrenia
- Healthy Volunteers
- Alzheimer's Disease
New Stem Cell Web Site to Focus on Traumatic Brain Injury, Spinal Cord Injury and Diabetes <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/prnews/090528/la23532.html?.v=1> - PR Newswire - Thu 10:30 am ET
Entest BioMedical, Inc., a newly formed wholly-owned subsidiary of San Diego-based Bio-Matrix Scientific Group, Inc. announced today the launch of its Web site to focus on new stem cell research, including a proposed research to develop a new therapeutic solution for traumatic brain injury using autologous adipose-derived stem cells representing a potential cure.
New Survey Highlights Growing Concern About Risk of Infection in Cancer Patients and Emerging Antibiotic Resistance <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/prnews/090527/la22782.html?.v=1> - PR Newswire - Wed 9:00 am ET
Year Initiative to Improve Infection Control in Vulnerable Cancer Patient Population
International Stem Cell Corporation Reports Positive Pre-Clinical Trial Results From Human Corneal Epithelial Cells <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/bw/090527/20090527005366.html?.v=1> - Business Wire - Wed 8:30 am ET
OCEANSIDE, Calif.----International Stem Cell Corporation , the first company to perfect a method of creating human "parthenogenetic" stem cells from unfertilized eggs, has received positive early results from animal trials designed to improve photorefractive keratectomy , a form of corrective laser eye surgery that offers an improved alternative to LASIK.
Medarex Announces Allowance of Investigational New Drug Application for Wholly-Owned Fully Human Anti-CXCR4 Antibody, MDX-1338 <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/prnews/090527/ph22695.html?.v=1> - PR Newswire - Wed 8:00 am ET
Clinical study planned for relapsed / refractory acute myelogenous leukemia-
Ceregene Presents Additional Clinical Data from Phase 2 Trial of CERE-120 for Parkinson's Disease <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/prnews/090527/sf22808.html?.v=1> - PR Newswire - Wed 7:00 am ET
Longer term follow-up indicates modest efficacy in primary and related endpoints --
Independent Data Monitoring Board Recommends Continuation to Completion of Genta's Phase 3 Trial of Genasense� in Advanced Melanoma <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/bw/090519/20090519005206.html?.v=1> - Business Wire - Tue May 19
BERKELEY HEIGHTS, N.J.----Genta Incorporated today announced that the independent Data Monitoring Board for AGENDA, a randomized Phase 3 trial of Genasense� in patients with advanced melanoma, has informed the Company that the study has passed its final futility analysis for progression-free survival .
Source - Google Health News:
Sanofi Pasteur Receives Order from US Government to Produce New ... <http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=109&STORY=/www/story/05-25-2009/0005031981&EDATE=>
PR Newswire (press release) - New York,NY,USA
Previously, we developed and licensed the first pre-pandemic vaccine for H5N1 and we look forward to further demonstrating our experience and expertise in ...
Russian researchers begin to make H1N1 vaccine <http://www.zeenews.com/news534338.html>
Zee News - Noida,Uttar Pradesh,India
Moscow, May 25: Russian researchers have begun preparations to create a vaccine against the H1N1 swine flu after a strain of the virus was received from a ...
Australia defends flu steps as global cases rise <http://www.google.com/hostednews/afp/article/ALeqM5g0yjeucxbIFK4f1zsVemLgdXvQjg>
AFP
SYDNEY (AFP) — Australia on Saturday defended its escalation of swine flu protection measures as global health chiefs said a vaccine could be ready as early ...
For Flu Vaccine, US Sets Aside $1 Billion <http://online.wsj.com/article/SB124303594956748749.html>
Wall Street Journal - USA
... with which it already has contracts to produce a pandemic vaccine -- contracts that were focused on the possibility of a pandemic of H5N1 avian flu. ...
Team hopes to start testing H1N1 vaccine within weeks <http://www.purdueexponent.com/index.php/module/Section/section_id/3?module=article&story_id=16681>
The Exponent - West Lafayette,IN,USA
... testing a vaccine on mice in the next couple of weeks. “We are trying to use a similar approach as we did with the H5N1 bird flu virus,” Mittal said. ...
H1N1 synthetic flu may be test run for H5N1 avian flu <http://onlinejournal.com/artman/publish/article_4730.shtml>
Online Journal - Silver Springs,FL,USA
However, there are misgivings in the international research community about administering an AH1N1 vaccine. The fear is that once a vaccination against ...
Source - Medical News Today:
What Is A Heart Attack? What Causes A Heart Attack? <http://www.medicalnewstoday.com/articles/151444.php>
If the heart muscle does not have enough blood (and consequently oxygen) it dies and a heart attack occurs. Another name for a heart attack is myocardial infarction, cardiac infarction and coronary thrombosis. According to Medilexicon's medical dictionary <http://www.medilexicon.com/medicaldictionary.php> , a heart attack is "infarction of a segment of heart muscle, usually due to occlusion of a coronary artery". (Infarction = the process whereby an area of dead tissue is caused by a loss of blood supply). A heart attack usually happens when a blood clot develops in one of the blood vessels that lead to the heart muscle (coronary arteries). The clot, if it is big enough, can stop the supply of blood to the heart. Blood supply to the heart can also be undermined if the artery suddenly narrows, as in a spasm.
http://www.medicalnewstoday.com/articles/151444.php
Call To Tackle The Causes Of Ageing Rather Than Treating The Effects <http://www.medicalnewstoday.com/articles/151516.php>
Tackling the very causes of ageing, rather than treating the symptoms in a piecemeal way offers the best prospects for dealing with the diseases and effects of ageing according to a public lecture being given at the Royal Society tonight. New research that offers up hope to improve health during ageing in humans, and to tackle a broad range of ageing-related diseases, will be presented tonight by Director of the UCL Institute of Healthy Ageing Professor Linda Partridge. She believes these scientific advances are inspiring a new wave in ageing research.
http://www.medicalnewstoday.com/articles/151516.php
MIT Researchers Develop Implantable Device To Monitor Cancer, Tissue Scaffold To Regrow Cartilage And Bone <http://www.medicalnewstoday.com/articles/151494.php>
Surgical removal of a tissue sample is now the standard for diagnosing cancer. And while biopsies are accurate, they only offer a snapshot of the tumor at a single moment in time. Monitoring a tumor for weeks or months after the biopsy, tracking its growth, and studying how it responds to treatment would be much more valuable, says Michael Cima, professor of materials science and engineering at the Massachusetts Institute of Technology, who has developed the first implantable device to do just that. "What this does is basically take the lab and put it in the patient," says Cima. The devices, which are designed to be implanted at the time of biopsy, could be tailored to monitor chemotherapy agents, allowing doctors to determine whether cancer drugs are reaching the tumors. They also can be designed to measure pH or oxygen levels, which would reveal a tumor's metabolism and response to therapy. The cylindrical, 5-millimeter implant contains magnetic nanoparticles coated with antibodies specific to the target molecules. Target molecules enter the implant through a semipermeable membrane, bind to the particles, and cause them to clump together -- a process that can be detected by MRI. The device is composed of polyethylene, which is commonly used in orthopedic implants. The semipermeable membrane, which allows target molecules to enter but traps the magnetic nanoparticles inside, is fabricated of polycarbonate, a compound used in many plastics. Cima's team studied the device by transplanting human tumors into mice, then using the implants to track levels of human chorionic gonadotropin, a hormone produced by human tumor cells, for more than a month. They reported their findings in ronics. Biosensors & Bioelectronics. <http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TFC-4W32KKR-5&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=6735e6b02700aedac852d1d3bb> Cima believes an implant to test for pH levels could be commercially available in a few years, followed by devices to test for complex chemicals such as hormones and drugs.
http://www.medicalnewstoday.com/articles/151494.php
Healing Wounds With Lasers <http://www.medicalnewstoday.com/articles/151449.php>
Researchers from around the world will present the latest breakthroughs in electro-optics, lasers and the application of light waves at the 2009 Conference on Lasers and Electro-Optics/International Quantum Electronics Conference (CLEO/IQEC) May 31 to June 5 at the Baltimore Convention Center in Baltimore.
http://www.medicalnewstoday.com/articles/151449.php
New Strategies For Cell Therapy To Regenerate Damaged Heart <http://www.medicalnewstoday.com/articles/151346.php>
Research undertaken at the Center for Applied Medical Research (CIMA) and the University Hospital of Navarra has shown that, in animal models, stem cells <http://www.medicalnewstoday.com/info/stem_cell/whatarestemcells.php> derived from bone marrow and adipose tissue enhance heart function after a cardiac attack. In concrete, bone marrow cells act on the damaged tissue, while fatty cells have the ability to transform themselves into both blood vessels and cardiac cells. The results obtained with rats are maintained over a long time period, explained biochemist Mr Manuel Mazo, principal researcher. When a person suffers a heart attack, the artery feeding the heart is obstructed The affected tissue dies and the scar tissue left des not contract. It is a serious problem as cardiac muscle does not regenerate, with grave consequences for the functional capacity of the heart, a situation which can trigger heart failure, explained the scientist.
http://www.medicalnewstoday.com/articles/151346.php
Alarming Rise In Deadly Skin Cancer Cases, UK <http://www.medicalnewstoday.com/articles/151317.php>
There has been an alarming rise in new cases of the deadliest form of skin cancer in the UK, with binge tanning cited as a main reason, said a leading cancer charity.
The number of UK people diagnosed with malignant melanoma, the potentially fatal type of skin cancer. has gone over the 10,000 barrier to reach an all time high of 10,400 according to figures released earlier today by Cancer Research UK.
http://www.medicalnewstoday.com/articles/151317.php <http://www.medicalnewstoday.com/articles/151317.php>
Source - MIT's Technology Review:
First Acoustic Superlens
http://www.technologyreview.com/biomedicine/22710/
What's the Point in Patenting Genes? <http://www.technologyreview.com/biomedicine/22704/?nlid=2055>
http://www.technologyreview.com/biomedicine/22704/?nlid=2055
Better Brain-Wave Analysis <http://www.technologyreview.com/biomedicine/22696/?nlid=2052>
http://www.technologyreview.com/biomedicine/22696/?nlid=2052
Entest BioMedical, Inc., a newly formed wholly-owned subsidiary of San Diego-based Bio-Matrix Scientific Group, Inc. announced today the launch of its Web site to focus on new stem cell research, including a proposed research to develop a new therapeutic solution for traumatic brain injury using autologous adipose-derived stem cells representing a potential cure.
New Survey Highlights Growing Concern About Risk of Infection in Cancer Patients and Emerging Antibiotic Resistance <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/prnews/090527/la22782.html?.v=1> - PR Newswire - Wed 9:00 am ET
Year Initiative to Improve Infection Control in Vulnerable Cancer Patient Population
International Stem Cell Corporation Reports Positive Pre-Clinical Trial Results From Human Corneal Epithelial Cells <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/bw/090527/20090527005366.html?.v=1> - Business Wire - Wed 8:30 am ET
OCEANSIDE, Calif.----International Stem Cell Corporation , the first company to perfect a method of creating human "parthenogenetic" stem cells from unfertilized eggs, has received positive early results from animal trials designed to improve photorefractive keratectomy , a form of corrective laser eye surgery that offers an improved alternative to LASIK.
Medarex Announces Allowance of Investigational New Drug Application for Wholly-Owned Fully Human Anti-CXCR4 Antibody, MDX-1338 <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/prnews/090527/ph22695.html?.v=1> - PR Newswire - Wed 8:00 am ET
Clinical study planned for relapsed / refractory acute myelogenous leukemia-
Ceregene Presents Additional Clinical Data from Phase 2 Trial of CERE-120 for Parkinson's Disease <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/prnews/090527/sf22808.html?.v=1> - PR Newswire - Wed 7:00 am ET
Longer term follow-up indicates modest efficacy in primary and related endpoints --
Independent Data Monitoring Board Recommends Continuation to Completion of Genta's Phase 3 Trial of Genasense� in Advanced Melanoma <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/bw/090519/20090519005206.html?.v=1> - Business Wire - Tue May 19
BERKELEY HEIGHTS, N.J.----Genta Incorporated today announced that the independent Data Monitoring Board for AGENDA, a randomized Phase 3 trial of Genasense� in patients with advanced melanoma, has informed the Company that the study has passed its final futility analysis for progression-free survival .
Source - Google Health News:
Sanofi Pasteur Receives Order from US Government to Produce New ... <http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=109&STORY=/www/story/05-25-2009/0005031981&EDATE=>
PR Newswire (press release) - New York,NY,USA
Previously, we developed and licensed the first pre-pandemic vaccine for H5N1 and we look forward to further demonstrating our experience and expertise in ...
Russian researchers begin to make H1N1 vaccine <http://www.zeenews.com/news534338.html>
Zee News - Noida,Uttar Pradesh,India
Moscow, May 25: Russian researchers have begun preparations to create a vaccine against the H1N1 swine flu after a strain of the virus was received from a ...
Australia defends flu steps as global cases rise <http://www.google.com/hostednews/afp/article/ALeqM5g0yjeucxbIFK4f1zsVemLgdXvQjg>
AFP
SYDNEY (AFP) — Australia on Saturday defended its escalation of swine flu protection measures as global health chiefs said a vaccine could be ready as early ...
For Flu Vaccine, US Sets Aside $1 Billion <http://online.wsj.com/article/SB124303594956748749.html>
Wall Street Journal - USA
... with which it already has contracts to produce a pandemic vaccine -- contracts that were focused on the possibility of a pandemic of H5N1 avian flu. ...
Team hopes to start testing H1N1 vaccine within weeks <http://www.purdueexponent.com/index.php/module/Section/section_id/3?module=article&story_id=16681>
The Exponent - West Lafayette,IN,USA
... testing a vaccine on mice in the next couple of weeks. “We are trying to use a similar approach as we did with the H5N1 bird flu virus,” Mittal said. ...
H1N1 synthetic flu may be test run for H5N1 avian flu <http://onlinejournal.com/artman/publish/article_4730.shtml>
Online Journal - Silver Springs,FL,USA
However, there are misgivings in the international research community about administering an AH1N1 vaccine. The fear is that once a vaccination against ...
Source - Medical News Today:
What Is A Heart Attack? What Causes A Heart Attack? <http://www.medicalnewstoday.com/articles/151444.php>
If the heart muscle does not have enough blood (and consequently oxygen) it dies and a heart attack occurs. Another name for a heart attack is myocardial infarction, cardiac infarction and coronary thrombosis. According to Medilexicon's medical dictionary <http://www.medilexicon.com/medicaldictionary.php> , a heart attack is "infarction of a segment of heart muscle, usually due to occlusion of a coronary artery". (Infarction = the process whereby an area of dead tissue is caused by a loss of blood supply). A heart attack usually happens when a blood clot develops in one of the blood vessels that lead to the heart muscle (coronary arteries). The clot, if it is big enough, can stop the supply of blood to the heart. Blood supply to the heart can also be undermined if the artery suddenly narrows, as in a spasm.
http://www.medicalnewstoday.com/articles/151444.php
Call To Tackle The Causes Of Ageing Rather Than Treating The Effects <http://www.medicalnewstoday.com/articles/151516.php>
Tackling the very causes of ageing, rather than treating the symptoms in a piecemeal way offers the best prospects for dealing with the diseases and effects of ageing according to a public lecture being given at the Royal Society tonight. New research that offers up hope to improve health during ageing in humans, and to tackle a broad range of ageing-related diseases, will be presented tonight by Director of the UCL Institute of Healthy Ageing Professor Linda Partridge. She believes these scientific advances are inspiring a new wave in ageing research.
http://www.medicalnewstoday.com/articles/151516.php
MIT Researchers Develop Implantable Device To Monitor Cancer, Tissue Scaffold To Regrow Cartilage And Bone <http://www.medicalnewstoday.com/articles/151494.php>
Surgical removal of a tissue sample is now the standard for diagnosing cancer. And while biopsies are accurate, they only offer a snapshot of the tumor at a single moment in time. Monitoring a tumor for weeks or months after the biopsy, tracking its growth, and studying how it responds to treatment would be much more valuable, says Michael Cima, professor of materials science and engineering at the Massachusetts Institute of Technology, who has developed the first implantable device to do just that. "What this does is basically take the lab and put it in the patient," says Cima. The devices, which are designed to be implanted at the time of biopsy, could be tailored to monitor chemotherapy agents, allowing doctors to determine whether cancer drugs are reaching the tumors. They also can be designed to measure pH or oxygen levels, which would reveal a tumor's metabolism and response to therapy. The cylindrical, 5-millimeter implant contains magnetic nanoparticles coated with antibodies specific to the target molecules. Target molecules enter the implant through a semipermeable membrane, bind to the particles, and cause them to clump together -- a process that can be detected by MRI. The device is composed of polyethylene, which is commonly used in orthopedic implants. The semipermeable membrane, which allows target molecules to enter but traps the magnetic nanoparticles inside, is fabricated of polycarbonate, a compound used in many plastics. Cima's team studied the device by transplanting human tumors into mice, then using the implants to track levels of human chorionic gonadotropin, a hormone produced by human tumor cells, for more than a month. They reported their findings in ronics. Biosensors & Bioelectronics. <http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TFC-4W32KKR-5&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=6735e6b02700aedac852d1d3bb> Cima believes an implant to test for pH levels could be commercially available in a few years, followed by devices to test for complex chemicals such as hormones and drugs.
http://www.medicalnewstoday.com/articles/151494.php
Healing Wounds With Lasers <http://www.medicalnewstoday.com/articles/151449.php>
Researchers from around the world will present the latest breakthroughs in electro-optics, lasers and the application of light waves at the 2009 Conference on Lasers and Electro-Optics/International Quantum Electronics Conference (CLEO/IQEC) May 31 to June 5 at the Baltimore Convention Center in Baltimore.
http://www.medicalnewstoday.com/articles/151449.php
New Strategies For Cell Therapy To Regenerate Damaged Heart <http://www.medicalnewstoday.com/articles/151346.php>
Research undertaken at the Center for Applied Medical Research (CIMA) and the University Hospital of Navarra has shown that, in animal models, stem cells <http://www.medicalnewstoday.com/info/stem_cell/whatarestemcells.php> derived from bone marrow and adipose tissue enhance heart function after a cardiac attack. In concrete, bone marrow cells act on the damaged tissue, while fatty cells have the ability to transform themselves into both blood vessels and cardiac cells. The results obtained with rats are maintained over a long time period, explained biochemist Mr Manuel Mazo, principal researcher. When a person suffers a heart attack, the artery feeding the heart is obstructed The affected tissue dies and the scar tissue left des not contract. It is a serious problem as cardiac muscle does not regenerate, with grave consequences for the functional capacity of the heart, a situation which can trigger heart failure, explained the scientist.
http://www.medicalnewstoday.com/articles/151346.php
Alarming Rise In Deadly Skin Cancer Cases, UK <http://www.medicalnewstoday.com/articles/151317.php>
There has been an alarming rise in new cases of the deadliest form of skin cancer in the UK, with binge tanning cited as a main reason, said a leading cancer charity.
The number of UK people diagnosed with malignant melanoma, the potentially fatal type of skin cancer. has gone over the 10,000 barrier to reach an all time high of 10,400 according to figures released earlier today by Cancer Research UK.
http://www.medicalnewstoday.com/articles/151317.php <http://www.medicalnewstoday.com/articles/151317.php>
Source - MIT's Technology Review:
First Acoustic Superlens
http://www.technologyreview.com/biomedicine/22710/
What's the Point in Patenting Genes? <http://www.technologyreview.com/biomedicine/22704/?nlid=2055>
http://www.technologyreview.com/biomedicine/22704/?nlid=2055
Better Brain-Wave Analysis <http://www.technologyreview.com/biomedicine/22696/?nlid=2052>
http://www.technologyreview.com/biomedicine/22696/?nlid=2052
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