Since August, 2005, this news digest has been a complimentary service of GBP Capital, a private equity firm investing in early to mid-stage life science companies. See www.gbpcap.com. The digest is published two to four days a week. If you have colleagues who would be interested in receiving this digest by email, they can be added to the list at: http://www.gbpcap.com/ <http://www.gbpcap.com/> . Also, the complete history of the entire content of all news articles in our digests since August, 2005 is searchable with Google's enterprise search engine at the same site.
Source - EurekAlert – Biology
Public Release: 22-May-2009
The challenges of avian influenza virus: Mechanism, epidemiology and control <http://www.eurekalert.org/pub_releases/2009-05/sicp-tco052209.php>
The latest special issue of Science in China Series C: Life Sciences focuses on the recent progress in the H5N1-related research field.
Contact: Li Jiyuan
ljy@scichina.org <mailto:ljy@scichina.org>
86-106-401-5399
Science in China Press <http://zh.scichina.com/english/>
Public Release: 21-May-2009
Protein predicts development of invasive breast cancer in women with DCIS, Penn study shows <http://www.eurekalert.org/pub_releases/2009-05/uops-ppd052109.php>
Women with ductal carcinoma in situ (DCIS) who exhibit an overexpression of the protein HER2/neu have a six-fold increase in risk of invasive breast cancer, according to a new study from the University of Pennsylvania School of Medicine. The results, published in the May issue of the journal Cancer Epidemiology, Biomarkers and Prevention, may help clinicians distinguish between DCIS that requires minimal treatment and DCIS that should be treated more aggressively.
Contact: Holly Auer
holly.auer@uphs.upenn.edu
215-200-2313
University of Pennsylvania School of Medicine <http://pennhealth.com/news>
Public Release: 21-May-2009
Gene therapy could expand stem cells' promise <http://news.med.cornell.edu/wcmc/wcmc_2009/05_21_09.shtml>
Once placed into a patient's body, stem cells intended to treat or cure a disease could end up wreaking havoc simply because they are no longer under the control of the clinician. But gene therapy has the potential to solve this problem, according to a perspective article from physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center published in a recent issue of the journal Cell Stem Cell.
Contact: John Rodgers
jdr2001@med.cornell.edu
212-821-0560
New York- Presbyterian Hospital/Weill Cornell Medical Center/Weill Cornell Medical College <http://www.med.cornell.edu>
Public Release: 21-May-2009
Genetic testing for breast or ovarian cancer risk may be greatly underutilized <http://www.eurekalert.org/pub_releases/2009-05/mgh-gtf052109.php>
Although a test for gene mutations known to significantly increase the risk of hereditary breast or ovarian cancer has been available for more than a decade, a new study finds that few women with family histories of these cancers are even discussing genetic testing with their physicians or other health care providers.
Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital <http://www.mgh.harvard.edu>
Public Release: 21-May-2009
LSUHSC research describes function of key protein in cancer spread <http://www.eurekalert.org/pub_releases/2009-05/lsuh-lrd052109.php>
Research led by David Worthylake, Ph.D., Assistant Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, may help lay the groundwork for the development of a compound to prevent the spread of cancer.
Contact: Leslie Capo
lcapo@lsuhsc.edu
504-568-4806
Louisiana State University Health Sciences Center <http://www.lsumc.edu>
Public Release: 21-May-2009
Diabetics' heart attack risk can be reduced, research finds <http://www.eurekalert.org/pub_releases/2009-05/uoc-dha052009.php>
People with diabetes who maintain intensive, low blood sugar levels are significantly less likely to suffer heart attacks and coronary heart disease, new research published today in the Lancet has shown.
Contact: Genevieve Maul
genevieve.maul@admin.cam.ac.uk
44-122-333-2300
University of Cambridge <http://www.cam.ac.uk>
Public Release: 21-May-2009
MicroRNA regulation of tumor-killing viruses avoids unwanted viral pathology <http://www.eurekalert.org/pub_releases/2009-05/plos-mro051809.php>
Scientists have determined how to produce replication-competent viruses with key toxicities removed, providing a new platform for development of improved cancer treatments and better vaccines for a broad range of viral diseases.
Contact: Emma Gilgunn-Jones
emma.gilgunn-jones@cancer.org.uk
44-207-061-8311
Public Library of Science <http://www.plos.org>
Public Release: 21-May-2009
'Happy hour' gene discovery suggests cancer drugs might treat alcoholism <http://www.eurekalert.org/pub_releases/2009-05/cp-gd051409.php>
A class of drugs already approved as cancer treatments might also help to beat alcohol addiction. That's the conclusion of a discovery in flies of a gene, dubbed "happy hour," that has an important and previously unknown role in controlling the insects' response to alcohol.
Contact: Cathleen Genova
cgenova@cell.com
617-397-2802
Cell Press <http://www.cellpress.com>
Public Release: 21-May-2009
Preventing ear infections in the future: Delivering vaccine through the skin <http://www.eurekalert.org/pub_releases/2009-05/asfm-pei051409.php>
An experimental vaccine applied the surface of the skin appears to protect against certain types of ear infections. Scientists from the Research Institute at Nationwide Children's Hospital in Columbus, Ohio, report their findings today at the 109th General Meeting of the American Society for Microbiology in Philadelphia.
Contact: Jim Sliwa
202-942-9297
American Society for Microbiology <http://www.asm.org>
Public Release: 21-May-2009
Key protein may explain the anti-aging and anti-cancer benefits of dietary restriction <http://www.eurekalert.org/pub_releases/2009-05/bifa-kpm051309.php>
A protein that plays a key role in tumor formation, oxygen metabolism and inflammation is involved in a pathway that extends lifespan by dietary restriction. The finding, by scientists at the Buck Institute, provides a new understanding of how dietary restriction contributes to longevity and cancer prevention and gives scientists new targets for developing and testing drugs that could extend the healthy years of life.
Contact: Kris Rebillot
krebillot@buckinstitute.org
415-209-2080
Buck Institute for Age Research <http://www.buckinstitute.org>
Public Release: 20-May-2009
MIT robotic therapy holds promise for cerebral palsy <http://www.eurekalert.org/pub_releases/2009-05/miot-mrt052009.php>
Over the past few years, MIT engineers have successfully tested robotic devices to help stroke patients learn to control their arms and legs. Now, they're building on that work to help children with cerebral palsy.
Contact: Elizabeth Thomson
thomson@mit.edu
617-258-5402
Massachusetts Institute of Technology <http://web.mit.edu/newsoffice>
Public Release: 20-May-2009
Strong immune response to new siRNA drugs in development may cause toxic side effects <http://www.eurekalert.org/pub_releases/2009-05/mali-sir052009.php>
Small synthetic fragments of genetic material called small interfering RNA (siRNA) can block production of abnormal proteins; however, these exciting new drug candidates can also induce a strong immune response, causing toxic side effects. Understanding how siRNA stimulates this undesirable immune activity, how to test for it, and how to design siRNA drugs to avoid it are critical topics explored in a timely review article published online ahead of print in Oligonucleotides.
Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2156
Mary Ann Liebert, Inc./Genetic Engineering News <http://www.liebertpub.com>
Public Release: 19-May-2009
U of Minnesota researcher develops brain-scanning process that holds promise for epilepsy treatments <http://www.eurekalert.org/pub_releases/2009-05/uom-uom051909.php>
University of Minnesota McKnight professor and director of Center for Neuroengineering Bin He has developed a new technique that has led to preliminary successes in noninvasive imaging of seizure foci. He's technique promises to play an important role in the treatment of epileptic seizures.
Contact: Patty Mattern
mattern@umn.edu
612-624-2801
University of Minnesota <http://www.umn.edu>
Public Release: 19-May-2009
A new way of treating the flu <http://www.eurekalert.org/pub_releases/2009-05/rpi-anw051909.php>
Promising new research announced by Rensselaer Polytechnic Institute could provide an entirely new tool to combat the flu. The discovery is a one-two punch against the illness that targets the illness on two fronts, going one critical step further than any currently available flu drug.
Contact: Gabrielle DeMarco
demarg@rpi.edu
518-276-6542
Rensselaer Polytechnic Institute <http://www.rpi.edu/News>
Source - Science Daily:
Please note: Due to the format restrictions of Science Daily articles, you must click on the URL (web address) below the article summary, rather than the article title.
Why Do People With Down Syndrome Have Less Cancer? Research In Mice And Human Stem Cells Suggests New Therapeutic Targets <http://www.sciencedaily.com/releases/2009/05/090520140359.htm>
Most cancers are rare in people with Down syndrome. The late cancer researcher Judah Folkman, M.D., proposed that the extra copy of chromosome 21 may contain a ...
http://www.sciencedaily.com/releases/2009/05/090520140359.htm
Gene Therapy Could Expand Stem Cells' Promise <http://www.sciencedaily.com/releases/2009/05/090521131317.htm>
May 22, 2009 — Once placed into a patient's body, stem cells intended to treat or cure a disease could end up wreaking havoc simply because they are no longer under the control of the clinician. But gene therapy ...
http://www.sciencedaily.com/releases/2009/05/090521131317.htm <http://www.sciencedaily.com/releases/2009/05/090521131317.htm>
Adult Stem Cells From Bone Marrow Made To Kill Metastatic Lung Cancer Cells In Mice <http://www.sciencedaily.com/releases/2009/05/090519172051.htm>
May 22, 2009 — Researchers have demonstrated the ability of adult stem cells from bone marrow (mesenchymal stem cells, or MSCs) to deliver a cancer-killing protein to tumors. The genetically engineered stem cells ...
http://www.sciencedaily.com/releases/2009/05/090519172051.htm <http://www.sciencedaily.com/releases/2009/05/090519172051.htm>
New Vaccine Strategy Might Offer Protection Against Pandemic Influenza Strains <http://www.sciencedaily.com/releases/2009/05/090518120954.htm>
May 22, 2009 — A novel vaccine strategy using virus-like particles could provide stronger and longer-lasting influenza vaccines with a significantly shorter development and production time than current ones, ...
http://www.sciencedaily.com/releases/2009/05/090518120954.htm <http://www.sciencedaily.com/releases/2009/05/090518120954.htm>
Triple Drug Combination Is Promising Option To Treat Metastatic HER2+ Breast Cancer <http://www.sciencedaily.com/releases/2009/05/090515093234.htm>
May 22, 2009 — Combining two chemotherapy drugs with trastuzumab to treat women who have metastatic HER2+ breast cancer may offer physicians another choice in their treatment ...
http://www.sciencedaily.com/releases/2009/05/090515093234.htm <http://www.sciencedaily.com/releases/2009/05/090515093234.htm>
Early Identification Of Dementia Increasingly Difficult <http://www.sciencedaily.com/releases/2009/05/090517152559.htm>
May 22, 2009 — If grandma seems to forget things, will she end up demented? These days, memory loss is one of the very few symptoms that may signal which 70-year-olds risk developing ...
http://www.sciencedaily.com/releases/2009/05/090517152559.htm <http://www.sciencedaily.com/releases/2009/05/090517152559.htm>
Bone Marrow Cell Therapy May Be Beneficial For Patients With Ischemic Heart Disease <http://www.sciencedaily.com/releases/2009/05/090519172103.htm>
May 22, 2009 — The injection of bone marrow cells into the heart of patients with chronic myocardial ischemia (reduced blood flow to some areas of the heart) was associated with modest improvements in blood flow ...
http://www.sciencedaily.com/releases/2009/05/090519172103.htm <http://www.sciencedaily.com/releases/2009/05/090519172103.htm>
New Strategies For Cell Therapy To Regenerate Damaged Heart <http://www.sciencedaily.com/releases/2009/05/090520055517.htm>
May 21, 2009 — In animal models, stem cells derived from bone marrow and adipose tissue enhance heart function after a cardiac ...
http://www.sciencedaily.com/releases/2009/05/090520055517.htm <http://www.sciencedaily.com/releases/2009/05/090520055517.htm>
Cancer Stem Cells May Be Related To Prognosis In Primary Breast Cancer <http://www.sciencedaily.com/releases/2009/05/090514221931.htm>
May 21, 2009 — Breast cancer patients who received chemotherapy prior to surgery had heightened levels of cancer-initiating stem cells in their bone marrow, and the level of such cells correlated to a tumor's lymph ...
http://www.sciencedaily.com/releases/2009/05/090514221931.htm <http://www.sciencedaily.com/releases/2009/05/090514221931.htm>
AIDS Patients With Serious Complications Benefit From Early Retroviral Use, Study Shows <http://www.sciencedaily.com/releases/2009/05/090516174342.htm>
May 21, 2009 — HIV-positive patients who don't seek medical attention until they have a serious AIDS-related condition can reduce their risk of death or other complications by half if they get antiretroviral ...
http://www.sciencedaily.com/releases/2009/05/090516174342.htm <http://www.sciencedaily.com/releases/2009/05/090516174342.htm>
Automated Analysis Of MR Images May Identify Early Alzheimer’s Disease <http://www.sciencedaily.com/releases/2009/05/090521171444.htm>
May 21, 2009 — Analyzing MRI studies of the brain may allow diagnosis of Alzheimer's disease and of mild cognitive impairment, a lesser form of dementia that precedes the development of Alzheimer's by several ...
http://www.sciencedaily.com/releases/2009/05/090521171444.htm <http://www.sciencedaily.com/releases/2009/05/090521171444.htm>
Genetic Testing For Breast Or Ovarian Cancer Risk May Be Greatly Underutilized <http://www.sciencedaily.com/releases/2009/05/090521131315.htm>
May 21, 2009 — Although a test for gene mutations known to significantly increase the risk of hereditary breast or ovarian cancer has been available for more than a decade, a new study finds that few women with ...
http://www.sciencedaily.com/releases/2009/05/090521131315.htm <http://www.sciencedaily.com/releases/2009/05/090521131315.htm>
Function Of Key Protein In Cancer Spread Described <http://www.sciencedaily.com/releases/2009/05/090521112829.htm>
May 21, 2009 — New research may help lay the groundwork for the development of a compound to prevent the spread of ...
http://www.sciencedaily.com/releases/2009/05/090521112829.htm <http://www.sciencedaily.com/releases/2009/05/090521112829.htm>
Old Diabetes Drug Teaches Experts New Tricks <http://www.sciencedaily.com/releases/2009/05/090514153136.htm>
May 20, 2009 — New research reveals that the drug most commonly used in type 2 diabetics who don't need insulin works on a much more basic level than once thought, treating persistently elevated blood sugar -- the ...
http://www.sciencedaily.com/releases/2009/05/090514153136.htm
Epigenetics: 100 Reasons To Change The Way We Think About Genetics <http://www.sciencedaily.com/releases/2009/05/090518111723.htm>
May 20, 2009 — Increasingly, biologists are finding that non-genetic variation acquired during the life of an organism can sometimes be passed on to offspring -- a phenomenon known as epigenetic inheritance. A new ...
http://www.sciencedaily.com/releases/2009/05/090518111723.htm
Surprise 'Spark' For Pre-cancerous Colon Polyps <http://www.sciencedaily.com/releases/2009/05/090514125154.htm>
May 19, 2009 — Researchers have studied the events leading to colon cancer and found that an unexpected protein serves as the "spark" that triggers formation of colon polyps, the precursors to cancerous ...
http://www.sciencedaily.com/releases/2009/05/090514125154.htm
Source - Health Day:
Health Highlights: May 21, 2009 <http://www.healthday.com/Article.asp?AID=627320>
- No Decline in Pregnant Women's Alcohol Use: CDC
- Japanese Women Have Longest Life Expectancy: WHO
- Chronic Ills Common Among Adults With Public Insurance: Study
- Many U.S. College Students Feel Stressed: Survey
- Costly Hospital Care Doesn't Guarantee Better-Quality Care: Study
- Young Children's Deaths Decline 27%: WHO
Patients under 44 were three times more likely to die, study finds.
Strict Blood Sugar Control Lowers Heart Risks in Diabetics
It prevents many complications of chronic disease, experts say.
Drug May Lessen Amputation Risk for Diabetics <http://www.healthday.com/Article.asp?AID=627317>
Researchers suggest that findings could alter treatment methods
A New Way to Get Chemo to Pancreatic Tumors <http://www.healthday.com/Article.asp?AID=627316>
Technique that doubles life span in mice may hold hope for people
Clinical Trials Update: May 21, 2009 <http://www.healthday.com/Article.asp?AID=627333>
- Heartburn
- Urticaria
- Epilepsy
- Migraine Headaches
- Depression in Adults
- Diabetic Peripheral Neuropathy
Source - Yahoo Biotech News:
Aastrom suspends trial following death of patient <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/ap/090522/us_aastrom_trial_suspended.html?.v=1> - AP - Fri 7:58 am ET
Stem cell drug developer Aastrom Biosciences Inc. said Friday it suspended a clinical trial after received a report that a patient died some time after treatment.
Stem Cell Stocks Mixed on Heavy Volume Action <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/indie/090521/1952_id.html?.v=1> - Indie Research - Thu 12:09 pm ET
Some stem cell stocks were up big on Thursday despite the market sell off.
Genzyme Submits All Information Requested by FDA for Lumizyme <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/bw/090521/20090521005700.html?.v=1> - Business Wire - Thu 11:57 am ET
CAMBRIDGE, Mass.----Genzyme Corporation announced today that it has submitted the final documentation to address all items in the FDA's complete response letter for Lumizyme™ , produced at the 2,000 L bioreactor
HGSI asks for FDA approval of anthrax drug ABthrax <http://us.rd.yahoo.com/finance/industry/news/mostpop/*http:/biz.yahoo.com/ap/090521/us_human_genome_sciences_anthrax.html?.v=1> - AP - Thu 8:00 am ET
Human Genome Sciences Inc. said Thursday it asked the Food and Drug Administration to approve ABthrax, a drug it is developing to treat inhaled anthrax.
Source - Google Health News:
UN, WHO heads meet vaccine manufacturers <http://www.alertnet.org/thenews/newsdesk/WHOm/9f5fefcf28911b7fbbc66a6e278b184d.htm>
Reuters AlertNet - London,England,UK
Influenza A(H1N1) has a very different clinical picture, which is so far mostly mild and self-limiting, unlike H5N1, which had a 50% to 60% mortality rate. ...
Nearly five billion doses of swine flu vaccine possible: WHO <http://www.google.com/hostednews/afp/article/ALeqM5hwEIni0qoBrPF13qfXTloU_cuenA>
AFP
Indonesia, one of the countries hit by H5N1 bird flu, raised concerns two years ago about access to subsequent commercially developed vaccines for people in ...
WHO, GSK Provide Update on Pandemic Flu Production <http://pharmtech.findpharma.com/pharmtech/Manufacturing/WHO-GSK-Provide-Update-on-Pandemic-Flu-Production/ArticleStandard/Article/detail/599059?contextCategoryId=35097>
Pharmaceutical Technology Magazine - Iselin,NJ,USA
GSK also said it will convert its intended donation to WHO of 50 million doses of H5N1 prepandemic vaccine to the new candidate A (H1N1) adjuvanted ...
Vical Advances H1N1 Pandemic Influenza (Swine Flu) Vaccine <http://www.tradingmarkets.com/.site/news/Stock%20News/2339254/>
Trading Markets (press release) - Los Angeles,CA,USA
... whether the company's DNA vaccine candidate will be effective in protecting humans against H5N1, H1N1, or any other strains of influenza; ...
Officials Fear New H1N1 Could Mix With Drug-Resistant Strains <http://www.redorbit.com/news/health/1692174/officials_fear_new_h1n1_could_mix_with_drugresistant_strains/>
RedOrbit - Dallas,TX,USA
... it had not changed its position on vaccine access for poor countries since the issue initially came to the fore in connection with the H5N1 bird flu. ...
Gene Therapy Could Expand Stem Cells' Promise <http://www.healthnewsdigest.com/news/Research_270/Gene_Therapy_Could_Expand_Stem_Cells_Promise.shtml>
HealthNewsDigest.com - New York,NY,USA
But gene therapy has the potential to solve this problem, according to a perspective article from physician-scientists at NewYork-Presbyterian ...
Solid Lipid Nanoparticles Could Be Used In Gene Therapy <http://www.sciencedaily.com/releases/2009/05/090518103225.htm>
Science Daily (press release) - USA
ScienceDaily (May 18, 2009) — Gene therapy offers hope in treating diseases such as cystic fibrosis and disorders of the retina, as well as with more common ...
Source - Medical News Today:
Seasonal Flu Vaccine Unlikely To Protect Against New H1N1 Says CDC <http://www.medicalnewstoday.com/articles/151042.php>
According to the US Centers for Disease Control and Prevention (CDC), vaccination with seasonal flu vaccines made for the 2005 to 2009 seasons is unlikely to protect people against infection by the new A (H1N1) swine flu virus. Scientists from the federal agency used banked blood samples taken before and after vaccination every year since 2005 and exposed them to the new swine flu virus. They reported the results of their investigations in the 19 May issue of their Morbidity and Mortality Weekly Report (MMWR).
http://www.medicalnewstoday.com/articles/151042.php
Genentech And Biogen Idec Submit Applications To The FDA For Rituxan For Most Common Type Of Adult Leukemia <http://www.medicalnewstoday.com/articles/151096.php>
Genentech, Inc. and Biogen Idec (Nasdaq:BIIB) announced that the companies submitted two supplemental Biologics License Applications (sBLAs) to the U.S. Food and Drug Administration (FDA) for Rituxan <http://www.medilexicon.com/drugs/rituxan.php> ® (rituximab) plus standard chemotherapy for people with previously untreated or treated chronic lymphocytic leukemia (CLL). The companies will request a priority review, and if granted, anticipate the FDA will make a decision within six months. CLL is the most common type of adult leukemia, accounting for one-third of all leukemias in the U.S. It is a slow-growing disease that occurs when too many abnormal white blood cells develop in the blood and bone marrow. The abnormal cells outnumber the normal white blood cells, making it difficult for the body to fight infection.
http://www.medicalnewstoday.com/articles/151096.php
The Difficulties Of Early Identification Of Dementia <http://www.medicalnewstoday.com/articles/150955.php>
If grandma seems to forget things, will she end up demented? These days, memory loss is one of the very few symptoms that may signal which 70-year-olds risk developing dementia. This is shown in a doctoral thesis at the Sahlgrenska Academy at the University of Gothenburg, Sweden. Several of the tests previously used to predict which elderly individuals risk developing dementia do not seem to work any longer. The thesis shows that memory loss is the only factor that can still be used to indicate who is at risk, although not among the very old.
http://www.medicalnewstoday.com/articles/150955.php
Team Tracks Nanotube Cancer Killers In Live Tissue <http://www.medicalnewstoday.com/articles/150872.php>
Nanotechnology scientists at two Arkansas research institutions have developed a method of detecting, tracking, and killing cancer cells in real time with carbon nanotubes. The discovery opens the prospect of a new, major front in the fight to eradicate cancer with promise for a new generation of cancer treatment beyond surgery, radiation, and chemotherapy.
http://www.medicalnewstoday.com/articles/150872.php
Revealing A Surprising Link Between Diabetes And Alzheimer's Disease <http://www.medicalnewstoday.com/articles/150847.php>
Blindness, heart disease, nerve damage, and kidney failure are not the only complications facing the nation's estimated 24 million people with diabetes <http://www.medicalnewstoday.com/info/diabetes/whatisdiabetes.php> . Although not widely known, those with the disease face up to double the risk of developing Alzheimer's disease (AD) than non-diabetics, according to an article scheduled for the May 18 issue of Chemical & Engineering News, ACS' weekly newsmagazine. C&EN senior editor Sophie Rovner explains in the article that people with diabetes tend to have a higher risk of getting AD, and possibly get it at an earlier age, than the general population. Five million people in the United States have Alzheimer's, a brain disorder that causes severe memory loss. Diabetes results from the body's inability to produce or use insulin. Newer research now suggests that insulin is critical for healthy nerve cells in the brain. As the hormone declines in the brains of people with Alzheimer's, so does their memory.
http://www.medicalnewstoday.com/articles/150847.php
Targeted Cancer Treatment Following Breakthrough In Radiotherapy <http://www.medicalnewstoday.com/articles/150774.php>
Current radiation therapy treatment damages a patient's healthy tissue as well as eradicating the tumour it is intended to destroy, making the treatment especially invasive and often causing nasty side effects. A new development in radiotherapy will enable a far more precise and accurate treatment for cancerous tumours by using real-time images to guide the radiation beam.
http://www.medicalnewstoday.com/articles/150774.php
New Study May Help Understand How Alzheimer's Robs Sufferers Of Episodic Memory <http://www.medicalnewstoday.com/articles/150639.php>
Memory loss is love's great thief. Those who suffer aren't just the ones who can't remember - family, friends and loved ones agonize over how to react when the disorder begins its often inexorable progress. Now, just-published research from scientists at the University of Georgia is offering new insights into how one kind of memory works. The study, published this week in the online edition of The Proceedings of the National Academy of Sciences, shows that laboratory rats have "episodic-like memory" and could open novel ways to study life-robbing loss of memory in humans.
http://www.medicalnewstoday.com/articles/150639.php
Individuals Who Have Low Levels Of 'Celebrex Gene' Are Resistant To Celebrex Treatment For Colon Tumor Prevention <http://www.medicalnewstoday.com/articles/150659.php>
A new study finds that individuals who have low expression of the "Celebrex gene," 15-PGDH, are actually resistant to Celebrex treatment when used to prevent colon cancer. The study, published in this week's issue of the Proceedings of the National Academy of Sciences (PNAS), is by Sanford Markowitz, M.D., Ph.D., the Markowitz-Ingalls Professor of Cancer Genetics at the Case Western Reserve University School of Medicine and an oncologist at the Ireland Cancer Center of University Hospitals Case Medical Center and his colleagues. "These findings have two important practical implications," said Markowitz, who is also an investigator in the Howard Hughes Medical Institute. "First, they suggest that measurement of 15-PGDH may identify which individuals are most likely to benefit from treatment with Celecoxib as a colon tumor preventative. Second, they suggest that identifying drugs that could increase 15-PGDH expression in the colon could be a potent new strategy for preventing development of tumors in the colon."
http://www.medicalnewstoday.com/articles/150659.php
Source - MIT's Technology Review:
How Down Syndrome Stops Cancer <http://www.technologyreview.com/biomedicine/22681/?nlid=2046>
http://www.technologyreview.com/biomedicine/22681/?nlid=2046
A Drug-Dispensing Lens <http://www.technologyreview.com/biomedicine/22680/?nlid=2046>
http://www.technologyreview.com/biomedicine/22680/?nlid=2046
Sending Genes into the Brain <http://www.technologyreview.com/biomedicine/22675/?nlid=2042>
http://www.technologyreview.com/biomedicine/22675/?nlid=2042
Healing the Heart with Bone-Marrow Cells <http://www.technologyreview.com/biomedicine/22676/?nlid=2042>
http://www.technologyreview.com/biomedicine/22676/?nlid=2042
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