Saturday, August 28, 2010

GBP Health / Biotech News Digest 08-26-2010

EurekAlert - Biology:

Public Release: 25-Aug-2010
Neuron
Scripps Research scientists uncover new mechanism of memory formation
Scientists from the Florida campus of the Scripps Research Institute have discovered a mechanism that plays a critical role in the formation of long-term memory. The findings shed substantial new light on aspects of how memory is formed, and could lead to novel treatments for memory disorders.

Contact: Mika Ono
mikaono@scripps.edu
858-784-2052
Scripps Research Institute

Public Release: 25-Aug-2010
Journal of Comparative Neurology
Research heralds potential for early diagnosis of degenerative brain disorders
A team of American scientists claim that a new method of testing for neurological diseases could provide doctors with a rapid and noninvasive method of diagnosing degenerative disorders. The research, published in The journal of Comparative Neurology, reveals that magnetic resonance spectroscopy can distinguish between different disorders in patients, allowing earlier diagnosis.

Contact: Ben Norman
Lifesciencenews@wiley.com
44-124-377-0375
Wiley-Blackwell

Public Release: 25-Aug-2010
Journal of Clinical Investigation
Liver cells created from patients' skin cells
By creating diseased liver cells from a small sample of human skin, scientists have for the first time shown that stem cells can be used to model a diverse range of inherited disorders. The University of Cambridge researchers' findings, which will hopefully lead to new treatments for those suffering from liver diseases, were published today in the Journal of Clinical Investigation.
Wellcome Trust, Medical Research Council

Contact: Genevieve Maul
Genevieve.maul@admin.cam.ac.uk
44-122-376-5542
University of Cambridge

Public Release: 25-Aug-2010
Nature
Use the common cold virus to target and disrupt cancer cells?
A novel mechanism used by adenovirus to sidestep the cell's suicide program, could go a long way to explain how tumor suppressor genes are silenced in tumor cells and pave the way for a new type of targeted cancer therapy, report researchers at the Salk Institute for Biological Studies in the Aug. 26, 2010, issue of Nature.

Contact: Gina Kirchweger
kirchweger@salk.edu
858-453-410-01340
Salk Institute

Public Release: 25-Aug-2010
Faraday Discussions
Microneedle, quantum dot study opens door to new clinical cancer tools
Researchers from North Carolina State University have developed extremely small microneedles that can be used to deliver medically-relevant nanoscale dyes called quantum dots into skin -- an advance that opens the door to new techniques for diagnosing and treating a variety of medical conditions, including skin cancer.
National Science Foundation, National Institutes of Health

Contact: Matt Shipman
matt_shipman@ncsu.edu
919-515-6386
North Carolina State University

Public Release: 23-Aug-2010
Nature Precedings
Health diagnosis made simpler
ASU researchers have developed and tested instrumentation they say will make disease diagnosis technically simpler, quicker and less costly. Using the shape of a drop biological fluid to focus a beam from a light-emitting diode, the device enables diagnosis of infectious diseases and unhealthy levels of protein.

Contact: Joe Kullman
joe.kullman@asu.edu
480-965-8122

Public Release: 23-Aug-2010
Biomaterials
A cluster bomb for cancer care
Dr. Dan Peer and Professor Ramona Margolit of Tel Aviv University have developed a nano-sized vehicle that can deliver chemotherapy drugs directly into cancer cells while avoiding interaction with healthy cells. "The vehicle is very similar to a cluster bomb," Dr. Peer says, and can be used to treat many different types of tumors, including lung, blood, colon and brain cancers.

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University

Source - Science Daily:

Please note : Due to the format restrictions of Science Daily articles, you must click on the URL (web address) below the article summary , rather than the article title.

Antiviral Gene Helps Suppress Jumping of AIDS Viruses Between Host Species

August 25, 2010 — The human AIDS viruses originated as viruses of apes and monkeys, respectively, yet little is known about whether or how these invaders adapted to the new genetic "environment" encountered in humans. ...

http://www.sciencedaily.com/releases/2010/08/100824171616.htm

Microneedle, Quantum Dot Study Opens Door to New Clinical Cancer Tools

August 25, 2010 — Researchers have developed extremely small microneedles that can be used to deliver medically-relevant nanoscale dyes called quantum dots into skin -- an advance that opens the door to new techniques ...

http://www.sciencedaily.com/releases/2010/08/100825093301.htm

Putting the Squeeze on Alzheimer's

August 25, 2010 — Brain cells exposed to a form of the amyloid beta protein, the molecule linked to Alzheimer's disease, become stiffer and bend less under pressure, researchers have ...

http://www.sciencedaily.com/releases/2010/08/100820101408.htm

Researchers Zero in on Protein That Destroys HIV

August 25, 2010 — Using a $225,000 microscope and the wisdom of Yogi Berra, researchers have identified the key components of a protein called TRIM5a that destroys HIV in rhesus monkeys. The finding could lead to ...

http://www.sciencedaily.com/releases/2010/08/100824121022.htm

Applying Stem Cell Technology to Liver Diseases

August 25, 2010 — Great excitement greeted the discovery a few years ago that certain cells from mice and humans could be reprogrammed to become inducible pluripotent stem cells (iPS cells) as they hold promise for ...

http://www.sciencedaily.com/releases/2010/08/100825131542.htm

Gene Therapy to Treat Epilepsy a Step Closer

August 25, 2010 — Current antiepileptic drugs have many side-effects, among others slowing down brain activity, which in turn reduces patients’ ability to react. These side-effects could be eliminated if genes ...

http://www.sciencedaily.com/releases/2010/08/100825093541.htm

New Cardiac Imaging Device Pioneered

August 24, 2010 — Researchers have for the first time developed a way to visualize coronary artery plaques vulnerable to rupture using multicolor computed tomography, an innovation that will lead to better and earlier ...

http://www.sciencedaily.com/releases/2010/08/100816110459.htm

Health Diagnosis Made Simpler: Bioengineers Design Device to Help Detect Diseases Quickly

August 24, 2010 — Researchers have developed and tested instrumentation they say will make disease diagnosis technically simpler, quicker and less costly. Using the shape of a drop biological fluid to focus a beam ...

http://www.sciencedaily.com/releases/2010/08/100823172333.htm

Math from the Heart: Simulating Stent Design and Coating

August 24, 2010 — Using computer models to study the strengths and weaknesses of different stent structures could help manufacturers optimize stent design and help doctors choose the right stents for their ...

http://www.sciencedaily.com/releases/2010/08/100823121937.htm

Double-Therapy Approach Effectively Inhibited Brain Cancer Recurrence

August 24, 2010 — Researchers have identified a novel approach of combining chemotherapy with a targeted therapy to decrease the recurrence of glioblastoma multiforme, the most common and aggressive brain ...

http://www.sciencedaily.com/releases/2010/08/100824132347.htm

Source - Health Day:

Health Highlights: Aug. 26, 2010

Seniors Face Large Drug Cost Increases: Report

Epidurals During Labor Protect Muscles: Study

FDA Warns About TimeOut Capsules

Traffic Crashes Cost $99 Billion Annually: Report

Millions Of Seniors May Have To Change Medicare Drug Plans: Analysis

Clinical Trials Update: Aug. 26, 2010

Osteoarthritis of the Knee

Schizophrenia

Depression

Clinical Trials Update: Aug. 25, 2010

Tinnitus

Hot Flashes (Postmenopausal Women)

Daily Aspirin Use

Source - Google Health News:

In Early Trial, Targeted Therapy Fights Advanced Melanoma
Experimental drug could help patients whose tumors carry particular gene mutation

Gene therapy firm seeks partners
Witney Gazette
By Maggie Hartford � GENE THERAPY company Oxford BioMedica is seeking partners to develop two of its potential treatments after half-year losses rose to ...

Scientists Look to Gene Therapy as Way to Boost Immune System Response to HIV
TheBody.com
The Los Angeles Times reports on the recent efforts of scientists to use gene therapy to strengthen the ability of patients living with HIV to fight off the ...

Non-Viral Gene Therapy Retards Retinal Degeneration
Medgadget.com
Bringing forth a more potent and enduring result will move us closer to clinical application of non-viral gene therapy,” said Kumar-Singh. ...

Source - Yahoo Biotech News:

Investors Eye Stem Cell Shares Amid Court Dispute - Indie Research - Thu 9:14 am ET
Earlier this week, U.S. District Judge Royce Lamberth hit the brakes an executive order aimed to remove "barriers to responsible research involving human stem cells," by ruling that millions in government grants can't be made.

Summary Box: J&J recalls 2 hip replacement systems - AP - 20 minutes ago
PERPETUAL PROBLEM: Johnson & Johnson announces its 11th recall of products since last September -- the second disclosed this week

Source - Medical News Today :

Insulin Resistance, Type 2 Diabetes Linked To Plaques Associated With Alzheimer's Disease

People with insulin resistance and type 2 diabetes appear to be at an increased risk of developing plaques in the brain that are associated withAlzheimer's disease, according to new research published in the August 25, 2010, issue of Neurology�, the medical journal of the American Academy of Neurology. Insulin resistance, or the stage before diabetes, happens when insulin, a hormone in the body, becomes less effective in lowering blood sugar.

http://www.medicalnewstoday.com/articles/198973.php

Novel Stem Cell Therapy From Cellonis Biotechnologies Can Help Children With Diabetes Get Back Their Normal Lives

Cellonis Biotechnologies, a Beijing and HK-based medical research and application company, has recorded some remarkable results in the treatment of a twelve-year-old boy with diabetes using their stem cell therapy in aBeijing partner hospital. He has completely regained his normal life, enjoying sports and school activities just like every other person his age, and has been free from injections and drugs for more than half a year. "Our whole family is delighted with this outcome," his mother commented in a Cellonis interview. "He is now no different from any other child at his school. There is no sign of diabetes anymore. He previously coughed a lot in spring and winter, but after the therapy we haven't seen him coughing at all. We are very pleased."

http://www.medicalnewstoday.com/articles/198840.php

Nano-Vehicle To Deliver Chemotherapy Treatments On Target

Chemotherapy, while an effective cancer treatment, also brings debilitating side effects such as nausea, liver toxicity and a battered immune system. Now, a new way to deliver this life-saving therapy to cancer patients - getting straight to the source of the disease - has been invented by Dr. Dan Peer ofTel Aviv University's Department of Cell Research and Immunology and the Center for Nano Science and Nano Technology together with Prof. Rimona Margalit of the Department of Biochemistry and Molecular Biology.

http://www.medicalnewstoday.com/articles/198736.php

Source - MIT's Technology Review :

Artificial Cornea Offers Long-Term Vision

http://www.technologyreview.com/biomedicine/26115/

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