Since August, 2005, this news digest has been a complimentary service of GBP Capital, a private equity firm investing in early to mid-stage life science companies. See www.gbpcap.com. The digest is published two to four days a week. If you have colleagues who would be interested in receiving this digest by email, they can be added to the list at: http://www.gbpcap.com/. Also, the complete history of the entire content of all news articles in our digests since August, 2005 is searchable with Google's enterprise search engine at the same site.
Nature MedicineNovel RNA interference screening technique identifies possible path for malignant glioma treatment
Researchers at the University of Massachusetts Medical School report on a cellular pathway in the deadly brain cancer malignant glioma, a pathway essential to the cancer's ability to grow -- and a potential target for therapy that would stop the cancer's ability to thrive.
Contact: Jim Fessenden
PublicAffairs@umassmed.edu
508-856-2000
University of Massachusetts Medical School
Nature Reviews EndocrinologyEndocrine-disrupting chemicals pose cancer risk
A review article describes the carcinogenic effects of endocrine-disrupting chemicals, including bisphenol A. Researchers express the need for more complex strategies for studying how these chemicals affect health but report that ample evidence supports changing public health and environmental policies to protect the public, particularly the developing fetus and women of reproductive age.
Parsemus Foundation, NIH/National Institute of Environmental Health SciencesContact: Siobhan Gallagher
617-636-6586
Tufts University, Health Sciences
Journal of Biological ChemistryProtein regulates enzyme linked to Alzheimer's disease
Researchers have zeroed in on a protein that may play a role in the progression of Alzheimer's disease. The team found that increasing levels of the protein prevented the accumulation of an enzyme linked to Alzheimer's. The strategy may lead to new treatments for the neurodegenerative disease.
NIH/National Institute on AgingContact: Siobhan Gallagher
617-636-6586
Tufts University, Health Sciences
110th General Meeting of the American Society for MicrobiologyBacteria as a predicter of colorectal cancer
Recent findings suggest that bacteria residing in the the human intestinal tract may be associated with an individual's risk of developing colon cancer. Scientists from the University of Florida present their research today at the 110th General Meeting of the American Society for Microbiology in San Diego, Calif.
Contact: Garth Hogan
ghogan@asmusa.org
American Society for Microbiology
110th General Meeting of the American Society for MicrobiologyMutant gum disease bacteria provide clue to treatment for Alzheimer's
A defective, mutant strain of the bacterium that causes gum disease could provide a clue to potential treatments for Alzheimer's, Parkinson's and a number of other diseases. Researchers from the University of Florida College of Dentistry report their findings today at the 110th General Meeting of the American Society for Microbiology in San Diego.
Contact: Garth Hogan
ghogan@asmusa.org
American Society for Microbiology
Journal of Clinical InvestigationWhat is the protein modification hypusine? A therapeutic target in diabetes
Underlying all forms of diabetes is dysfunction of cells in the pancreas known as beta cells. The dysfunction is, in part, a result of inflammation mediated by soluble immune molecules known as cytokines. New research now provides greater understanding of the molecular mechanisms by which beta cells respond to cytokines and could aid in the development of protective therapeutics.
National Institutes of Health, Senesco Technologies Inc., Ball Brothers FoundationContact: Karen Honey
press_releases@the-jci.org
734-546-5242
Journal of Clinical Investigation
New Cancer Vaccine Starves Tumours of Blood
May 25, 2010 — A DNA-vaccine that restricts the supply of blood to tumors has been developed by scientists in Sweden. The vaccine slows the growth of breast cancer tumors in ...
http://www.sciencedaily.com/releases/2010/05/100524111705.htm
Drinking Fewer Sugar-Sweetened Beverages May Lower Blood Pressure
May 25, 2010 — Drinking fewer sugar-sweetened beverages -- a leading source of added sugar in the US diet -- may lower blood pressure, according to new ...
http://www.sciencedaily.com/releases/2010/05/100524161244.htm
To Attack H1N1, Other Flu Viruses, Gold Nanorods Deliver Potent Payload
May 25, 2010 — Future pandemics of seasonal flu, H1N1 and other drug-resistant viruses may be thwarted by a potent, immune-boosting payload that is effectively delivered to cells by gold nanorods, scientists ...
http://www.sciencedaily.com/releases/2010/05/100524161335.htm
Cancer-Targeting Virus Delivered by IV Is Successful in Treating Advanced Cancers, Research Finds
May 24, 2010 — Intravenous delivery of a cancer-targeting virus is successful in destroying cancer cells that have spread throughout the body, according to new ...
http://www.sciencedaily.com/releases/2010/05/100524105050.htm
Four Biomarkers Important in Colerectal Cancer Treatment Prognosis Discovered
May 24, 2010 — The science of microRNAs continues to generate new insights into cancer and disease treatment. New research shows that four specific miRNAs will help predict which patients are more likely to develop ...
http://www.sciencedaily.com/releases/2010/04/100419090947.htm
Routine Breast Cancer Biopsy Might Predict Lymph Node Cancer Spread
May 24, 2010 — Predicting breast cancer spread from a sentinel lymph node removed during surgery is a hit or miss affair, say researchers: there are still many false negatives, which means the node, when analyzed ...
http://www.sciencedaily.com/releases/2010/04/100418155430.htm
Lung Cancer: Biopsy-Based Study Tilts Field Toward Personalized Treatment
May 24, 2010 — The first lung cancer clinical trial to guide targeted therapies to patients based on molecular signatures in tumor biopsies is a step toward personalized care and more effective, efficient clinical ...
http://www.sciencedaily.com/releases/2010/04/100419113652.htm
Early Detection of Parkinson's Disease by Voice Analysis
May 24, 2010 — A new technique assisting in early diagnosis of Parkinson's disease has been developed. It involves analysis of voice and ...
http://www.sciencedaily.com/releases/2010/04/100419102927.htm
Gene Therapy Plus Chemotherapy Ups Odds for Success in Treating 'Bubble Boy' Disease
May 24, 2010 — Gene therapy combined with chemotherapy may lead to immune system improvement in patients with 'bubble boy' disease, according to a new ...
http://www.sciencedaily.com/releases/2010/05/100524105403.htm
Tapping P53 to Kill Cancer Cells More Effectively While Sparing Normal Cells
May 24, 2010 — A new finding by researchers in Singapore makes a unique method of cancer treatment now feasible. Their work offers new insight on how to tap on the properties of p53, the "guardian of the genome," ...
http://www.sciencedaily.com/releases/2010/05/100524101337.htm
Gene Therapy May Be Effective in Treating Pulmonary Arterial Hypertension
May 23, 2010 — Gene therapy has been shown to have positive effects in rat models of pulmonary arterial hypertension (PAH), according to researchers at the University of Adelaide in ...
http://www.sciencedaily.com/releases/2010/05/100519112607.htm
Exercise May Keep Cancer Patients Healthier During, After Treatment
May 22, 2010 — Breast and prostate cancer patients who regularly exercise during and after cancer treatment report having a better quality of life and being less fatigued, according to ...
http://www.sciencedaily.com/releases/2010/05/100520213110.htm
Health Highlights: May 25, 2010
- Calorie Counts at Some Restaurants 'Off the Charts'
- States Can Do More to Promote Exercise: CDC Report
- Dangerous Hospital Bacterium Spreads in Air: Study
- States Banning Synthetic ' K2' Pot
- Thinnest Shoppers Found at High-End Food Stores
Moderate Drinking May Protect Brain From Alzheimer's
Non-smoking women seem to benefit the most, study finds
Clinical Trials Update: May 25, 2010
- Hepatitis C
- Type 2 Diabetes
- Gout
Genzyme gets FDA approval for Lumizyme - AP - 1 hour, 10 minutes ago
Federal regulators approved Genzyme's drug to treat a muscle development disease, sending shares of the Biotechnology company up 6 percent Tuesday.
Neurocrine jumps on data from endometriosis study - AP - Tue 11:57 am ET
Shares of Neurocrine Biosciences Inc. surged to a new 52-week high Tuesday after the company announced its gynecological drug candidate met established goals in a mid-stage clinical trial.
Abbott's Groundbreaking Bioresorbable Technology Continues to Demonstrate Exceptional Clinical Results - PR Newswire - Tue 10:05 am ET
Abbott today announced positive six-month results from the first 45 patients enrolled in the second stage of the ABSORB trial, which was presented during the Late-Breaking Clinical Trials session at the EuroPCR 2010 conference.
Cancer-Targeting Virus Delivered by IV Is Successful in Treating Advanced ...
Science Daily (press release)
“This opens up a whole new world of systemic approaches to therapy.” Gene therapy has been used before to fight cancer, but previous treatments were limited ...
Inhaling chemo brings drugs straight to lung cancer
DOTmed.com (press release)
Inhaling a potent mix of anticancer and gene therapy drugs shrinks lung cancer tumors while decreasing toxicity to other organs, a new study finds. ...
Gene Therapy Might Treat 'Bubble Boy' Disease
BusinessWeek
By Randy Dotinga FRIDAY, May 21 (HealthDay News) -- Scientists report that they've successfully used gene therapy to treat a small number of patients with ...
Researchers Develop Device To Predict Diabetic Wound Healing
Complex wounds affect more patients in the United States than heart attack and stroke combined, and five to seven million Americans with complex wounds account for over $20 billion in healthcare expenditures. About 150,000 amputations a year result from complex wounds, while about 80,000 are attributed to diabetes and peripheral arterial disease. There are currently no established methods for early detection of wound healing, or for precise identification of healing progress. Wound size is the only accepted indicator despite its variability and the fact that is reflects only what is happening on the surface. A new breakthrough device developed by researchers can change the current landscape of chronic wound management. Researchers at Drexel University's School of Biomedical Engineering, Science and Health Systems developed a prototype device that measures the level of oxygenated and deoxygenated hemoglobin within and under a wound and compares it to a control/non-wound site of the same patient. Based on a human study at the Wound Clinic of the Drexel College of Medicine, the time course of oxygenated hemoglobin change was found to be a strong indicator of wound healing.
http://www.medicalnewstoday.com/articles/189788.php
A New Cancer Vaccine Starves Tumours Of Blood
A DNA-vaccine that restricts the supply of blood to tumours has been developed by scientists at the Swedish medical university Karolinska Institutet. The vaccine slows the growth of breast cancertumours in mice. If a cancer tumour is to become larger than a few millimetres it must be able to stimulate the formation of new blood vessels, in order to secure the supply of oxygen and nutrients. Drugs that prevent the growth of blood vessels are thus a potential treatment alternative for tumours.
http://www.medicalnewstoday.com/articles/189726.php
New Step In Protein Production Could Explain Cellular Response To Stress
UK scientists found a new step in how cells make protein which could explain how they respond to stress, such as starvation and being attacked by viruses. Drs Graham Pavitt and Martin Jennings from the Faculty of Life Sciences at the University of Manchester, described their findings in a paper published online on 20 May in the journal Nature.
http://www.medicalnewstoday.com/articles/189691.php
Type 2 Diabetes Linked To Increased Risk Of Many Cancers But Not Prostate Cancer
A large study covering around half of all Sweden's type 2 diabetes patients found they had a higher risk of developing a number of cancers compared to the general population, but this was not the case for prostate cancer , where type 2 diabetes patients curiously showed a lower risk. You can read about the study, led by the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) in Heidelberg, online in the 17 May issue of The Oncologist.
http://www.medicalnewstoday.com/articles/189652.php
No comments:
Post a Comment
Note: Only a member of this blog may post a comment.