Source - EurekAlert – Biology:
Public Release: 28-Aug-2009
UF scientists construct 'off switch' for Parkinson therapy
Addressing safety concerns related to potential gene therapies for Parkinson's disease, researchers at the University of Florida's McKnight Brain Institute have constructed a gene transfer therapy that can be inhibited with a common antibiotic. Experiments in rats show that the gene therapy product can be completely shut off, indicating for the first time that genes that have been irrevocably delivered to the brain to treat Parkinson's can be regulated.
Contact: John Pastor
jdpastor@ufl.edu
352-273-5815
University of Florida
Public Release: 27-Aug-2009
U-Iowa improves delivery of cancer-fighting molecules
University of Iowa researchers have modified siRNA, a type of genetic material that can block potentially harmful activity in cells, so that it can be injected into the bloodstream and impact targeted cells while producing fewer side effects. The findings could make it easier to create large amounts of targeted therapeutic siRNAs for treating cancer and other diseases.
Contact: Becky Soglin
becky-soglin@uiowa.edu
319-356-7127
University of Iowa
Public Release: 27-Aug-2009
Beta-blockers and stroke -- new insights into their use for older people
Research conducted at Leicester reveals effects of blood pressure drugs on cardiovascular disease.
Contact: Bryan Williams
bw17@le.ac.uk
44-116-252-3182
University of Leicester
Public Release: 27-Aug-2009
Immune defect is key to skin aging
Scientists have discovered why older people may be so vulnerable to cancer and infections in the skin. The team has shown in human volunteers that defective immunity in the skin is caused by an inability to mobilize essential defenses that would otherwise recognize threats and clear them before irreparable damage is done. This discovery could be important for preventing, managing or treating many age-related skin health problems.
Contact: Nancy Mendoza
press.office@bbsrc.ac.uk
44-179-341-3355
Biotechnology and Biological Sciences Research Council
Public Release: 27-Aug-2009
Chemotherapy resistance: Checkpoint protein provides armor against cancer drugs
Cell cycle checkpoints act like molecular tripwires for damaged cells, forcing them to pause and take stock. Leave the tripwire in place for too long, though, and cancer cells will press on regardless, making them resistant to the lethal effects of certain types of chemotherapy, according to researchers at the Salk Institute for Biological Studies.
Contact: Mauricio Minotta
minottta@salk.edu
858-453-410-01371
Salk Institute
Public Release: 27-Aug-2009
'Fatostatin' is a turnoff for fat genes
A small molecule earlier found to have both anti-fat and anti-cancer abilities works as a literal turnoff for fat-making genes, according to a new report in the Aug. 28 issue of the journal Chemistry and Biology, a Cell Press journal.
Contact: Cathleen Genova
cgenova@cell.com
617-397-2802
Cell Press
Source - Science Daily:
Please note: Due to the format restrictions of Science Daily articles, you must click on the URL (web address) below the article summary, rather than the article title.
Washing Away Painful Wounds
August 28, 2009 — A new device uses a solution to wash away necrotic tissue, bathing a chronic wound while keeping bacteria ...
http://www.sciencedaily.com/releases/2009/08/090826152601.htm
How Safe Or Unsafe Are Medical Imaging Procedures?
August 28, 2009 — In a new study of nearly one million adults between the ages of 18 and 64, nearly 70 percent of participants underwent at least one medical imaging procedure between July 2005 and December 2007, ...
http://www.sciencedaily.com/releases/2009/08/090826191837.htm
Predicting Cancer Prognosis
August 28, 2009 — Researchers have developed a novel methodology to extract microRNAs from cancer tissues. They optimized a new protocol for extracting miRNAs from formalin-fixed paraffin-embedded ...
http://www.sciencedaily.com/releases/2009/08/090827123216.htm
The Path To New Antibiotics
August 28, 2009 — Researchers have demonstrated that an enzyme that is essential to many bacteria can be targeted to kill dangerous pathogens. In addition, investigators discovered chemical compounds that can inhibit ...
http://www.sciencedaily.com/releases/2009/08/090827131830.htm
Finnish Scientists Discover Nerve Growth Factor With Therapeutic Potential In Parkinson's Disease
August 28, 2009 — Scientists Finland have reported promising new results with potential implications for the treatment of Parkinson's disease. They have been studying the impacts of nerve growth factors in the ...
http://www.sciencedaily.com/releases/2009/08/090828103924.htm
Tool To Rank Death Rates Developed
August 27, 2009 — Have you ever wondered what the chances are that you may die in the next year? Would it be from illness or an accident? Is it something you can control? Or is it completely out of your hands? A new ...
http://www.sciencedaily.com/releases/2009/08/090826164907.htm
'Hedgehog' Pathway May Hold Key To Anti-cancer Therapy
August 27, 2009 — Scientists in Switzerland have discovered a way to block the growth of human colon cancer cells, preventing the disease from reaching advanced ...
http://www.sciencedaily.com/releases/2009/08/090826191839.htm
Newly Discovered Mechanism In Cell Division Has Implications For Chromosome's Role In Cancer
August 27, 2009 — Errors in cell division can cause mutations that lead to cancer, and a new study could shed light on the role of chromosome abnormalities in uncontrolled cell replication. Researchers uncovered the ...
http://www.sciencedaily.com/releases/2009/08/090817143608.htm
Researchers Identify New, Cancer-causing Role For Protein
August 27, 2009 — The mainstay immune system protein TRAF6 plays an unexpected, key role activating a cell signaling molecule that in mutant form is associated with cancer growth, researchers report in ...
http://www.sciencedaily.com/releases/2009/08/090827141356.htm
Chemotherapy Resistance: Checkpoint Protein Provides Armor Against Cancer Drugs
August 27, 2009 — Cell cycle checkpoints act like molecular tripwires for damaged cells, forcing them to pause and take stock. Leave the tripwire in place for too long, though, and cancer cells will press on ...
http://www.sciencedaily.com/releases/2009/08/090827123208.htm
Source - Health Day:
Health Highlights: Aug. 28, 2009
- Gulf Coast Births Fell Post-Katrina
- UN Wary of Swine Flu in Birds
- Pregnant Women, New Parents Urged to Get Swine Flu Vaccine
- U.S. Issues New Guidelines for Treating Children With HIV
Most untreated Ugandans infected with type D were affected, study found
Ankle Circulation Could Warn of Future Strokes
Quick test may detect peripheral artery disease, research shows
Clinical Trials Update: Aug. 28, 2009
- Gout
- Depression
- Triglycerides
Survival has significantly increased, research shows
Clinical Trials Update: Aug. 27, 2009
- Flu Vaccine
- Coronary Heart Disease
- Osteoarthritis
Source - Yahoo Biotech News:
FDA Advisory Committee to Discuss Genzyme's Clolar for Adult AML on September 1
CAMBRIDGE, Mass.----Genzyme Corporation announced today that its supplemental New Drug Application for Clolar® will be discussed Tuesday, September 1 at a public meeting of the FDA’s Oncologic Drugs Advisory Committee in Silver Spring, Maryland.
Sinovac wins flu vaccine contract in China
Sinovac Biotech Ltd. said Friday it won a contract through the Beijing Public Health Bureau to supply the seasonal flu vaccine Anflu in Beijing.
Source - Google Health News:
The global swine flu pandemic 1: exploring the background to ...
Nursing Times
Although mainly only infecting birds, the current genotype of HPAI H5N1 can infect humans and, as of May 2009, 431 confirmed human cases of avian influenza ...
Hundreds affected by H1N1 virus
Technique
Pandemic flu preparations have been in place at Tech since 2006 during the avian flu (H5N1) outbreaks. In addition, CDC officials have trained Tech health ...
Health, Fitness and Drugs : Avian Flu: Do You Want the Good News ...
SkyNewswire.com
In other words, the virus came from birds - it is believed - and a virus similar to this one -called the "H5N1" (a form of avian flu virus). Its origins? ...
Nanotechnology-based gene therapy technique could fight late-stage ...
Nanowerk LLC - 5 hours ago
In preclinical studies, the investigators found that the gene therapy treatment was equally as effective and in some cases more effective than the ...
Source - Medical News Today:
Cumulative Radiation Exposure From Imaging Scans Should Be Weighed Against The Benefits Say Researchers
US researchers found that repeated exposure to ionizing radiation from medical imaging such as x-rays, fluoroscopy, computed tomography (CT) and nuclear medicine scans can accumulate over time to substantial cancer-causing doses, and recommend that doctors and patients always weigh up the benefits of imaging against the risks. The study was the work of lead author Dr Reza Fazel and colleagues and appears in the 27 August issue of the New England Journal of Medicine, NEJM. Fazel, a cardiologist in the Department of Medicine at Emory University School of Medicine in Atlanta, Georgia, told the media that:
http://www.medicalnewstoday.com/articles/162170.php
Ochsner Replaces Heart Valve Without Open Heart Surgery
On Tuesday, August 11, 2009, an 82-year old New Orleans resident with severe aortic stenosis successfully had a heart valve replaced at Ochsner Medical Center using the same technique as angioplasty, a far cry from the traditional open heart procedure. Patients who are considered high-risk or non-operable for conventional open heart valve surgery now have a potential new research option available regionally only through The John Ochsner Heart & Vascular Institute. Ochsner Medical Center is the only hospital in the Gulf South selected to participate as an FDA investigative site in the PARTNER (Placement of AoRTic traNscathetER valves) clinical trial, evaluating the Edwards SAPIEN transcatheter aortic heart valve in patients who are at high risk for open heart surgery and surgical valve repair.
http://www.medicalnewstoday.com/articles/162148.php
Many Hospitals Are Not Ready For H1N1: Nurse Survey Shows Deficiencies In Hospital Swine Flu Readiness
A patient health and safety survey of 190 American hospitals from coast to coast compiled by registered nurses in nine different states finds that a disturbing number of our nation's healthcare facilities are not prepared for the coming H1N1/swine flu
http://www.medicalnewstoday.com/articles/162032.php
Scientists Discover Cause Of Breast Cancer Spread
Scientists in London have identified a molecule that could be helping breast cancer
http://www.medicalnewstoday.com/articles/162077.php
Source - MIT's Technology Review:
A Beacon to Guide Cancer Surgery
http://www.technologyreview.com/biomedicine/23311/
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